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teal and brown molecular complexes

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.  The finding clarifies an important aspect of cell biology, and may have clinical implications, since this messenger RNA modification, known as m6A, is the target of an emerging class of cancer treatments.

Messenger RNA (mRNA)—the molecule that carries genetic instructions to make proteins—is...

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A group of people cutting a ceremonial ribbon

As a third-year medical student, Stone Streeter cut his teeth during his medical education at Weill Cornell Medicine while living in the institution’s student housing—first at Olin Hall during his classroom instruction, then at Lasdon House for his clerkships. As he eyes his last year at Weill Cornell Medical College, he’s preparing for yet another move: to the Feil Family and Weill Family Residence Hall.

“Now, I’m standing here today, a mosaic of past experiences, ready to tackle the...

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Vincent du Vigneaud 2025
2025 du Vigneaud co-chairs

Vincent du Vigneaud Symposium co-chairs Jian Zheng and Tzippora Chwat-...

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group of doctors sitting around a table

Teams of health care providers called Accountable Care Organizations participating in the Medicare Shared Savings Program have saved Medicare between $4.1 billion and $8.1 billion from 2012 through 2019, according to a new study from Weill Cornell Medicine investigators. The study, published April 28 in JAMA, is thought to be the first to investigate the long-term impact of the program.

Launched in 2012, the...

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awards

Three distinguished Weill Cornell Medicine physician-scientists, Dr. Matthew Greenblatt, Dr. Lishomwa Ndhlovu and Dr. Sallie Permar, have been elected to the prestigious Association of American Physicians (AAP).

Regarded as one of the top honors in the field of health and medicine, election to the AAP recognizes physician-scientists who exhibit excellence in the pursuit of medical knowledge and the advancement of basic or translational science through experimentation and discovery and...

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six people standing in front of a building with a sign reading "Tuberculosis and Clinical Trial Unit (CTU) Laboratory"

In 2023, tuberculosis (TB) killed about 1.25 million people worldwide, more than any other infectious disease on Earth — even though it is curable. Months- or even years-long regimens of potent antibiotics can eradicate the Mycobacterium tuberculosis bacteria. And in about...

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blue and red drawing of different types of viruses

A major new effort at Weill Cornell Medicine seeks to catalog the normal human virome, the immense ecosystem of viruses that lives in and on us. The work, part of a multi-institution collaboration called Viromes Across Space and Time (VAST), supported by the National Institute on Aging, part of the National Institutes of Health, will pioneer new techniques, illuminate a crucial aspect of human biology that was impossible to study before, and establish a baseline set of data that could help...

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glioblastoma circuits

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell Medicine researchers. The findings, published April 3 in Molecular Cell, offer a new way to think about cancer beyond gene mutations,...

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chromosomes with telomeres

A new study from Weill Cornell Medicine provides insights into how cells maintain the tiny end caps of chromosomes as they divide, a key process in keeping cells healthy. Using yeast, the researchers reveal protein interactions that could explain how the enzyme telomerase is tightly regulated to prevent cells from dividing uncontrollably or aging prematurely. The preclinical study, published April 17 in Nucleic...

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Cartoon image of green figures blocking blue figures from accessing a castle turret with cancer cells

Bacteria naturally present in the human intestine, known as the gut microbiota, can transform cholesterol-derived bile acids into powerful metabolites that strengthen anti-cancer immunity by blocking androgen signaling, according to a preclinical study led by Weill Cornell Medicine investigators. The study was published on April 15 in Cell.

...
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Two Caucasian men in dark-colored business attire sitting on sofas

Nearly 200 scientists, investors and industry representatives attended Weill Cornell Medicine’s 2025 Biomedical Innovation Conference (“BioInnovate”) April 1, sharing their startup journeys and experiences nurturing biomedical advances into health care products and companies.

The conference, hosted in the institution’s Uris Auditorium, featured a fireside chat with venture capitalist Alex Gorsky, general partner at investment firm ICONIQ Growth and the former...

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Dr. Sabine Ehrt

(New York, April 14, 2025)—Dr. Sabine Ehrt, an internationally renowned leader in tuberculosis research, has been appointed chair of the Department of Microbiology and Immunology at Weill Cornell Medicine, effective July 1.

The department, which is comprised of microbiologists and immunologists, focuses on the body’s interaction with microbes like...

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leadership

Thriving as a woman in academic medicine requires blending resilience, authenticity and community while nurturing passions and people, said Dr. Helen W. Boucher, dean of Tufts University School of Medicine and chief academic officer of Tufts Medicine, in her keynote address April 10 for Weill Cornell Medicine’s seventh annual Diversity Week.   

Dr. Boucher, who is also a professor of medicine at Tufts, delivered the Women in Medicine and...

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gloved hand holding lab tube

A new, error-corrected method for detecting cancer from blood samples is much more sensitive and accurate than prior methods and may be useful for monitoring disease status in patients following treatment, according to a study by Weill Cornell Medicine and New York Genome Center investigators. The method, based on whole-genome sequencing of DNA, also represents an important step toward the goal of routine blood test-based screening for early cancer...

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two men standing next a woman in an auditorium

Diversity is a tool for truth, not political agendas, said Vincent D. Rougeau,  president of the College of the Holy Cross, in his keynote address April 7 for Weill Cornell Medicine’s seventh annual Diversity Week. 

Rougeau delivered the Elizabeth A. Wilson-Anstey, EdD Lecture, “Why Commitment to Diversity Still Matters,” in Uris Auditorium as part...

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Diversity awards 2025

Weill Cornell Medicine’s Celebration of Diversity honored leaders who go beyond their official roles, dedicating time, energy and empathy to build inclusive environments. The ceremony, part of the institution’s seventh annual Diversity Week, was held April 7 in Griffis Faculty Club.

“This is one of the most important evenings of the year at Weill Cornell Medicine,” said  Dr. Robert A. Harrington, the...

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Di Lorenzo Ceremides


New research from Weill Cornell Medicine has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes—not the presence of certain fats, but their suppression. The study, published Feb. 25 in Nature Communications, challenges the conventional belief that a type of fat called ceramides accumulates in blood vessels causing inflammation and health risks. Instead, their preclinical findings...

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DIPG

A Phase I clinical trial demonstrated that a targeted approach to treating a deadly brain tumor in children called diffuse intrinsic pontine glioma (DIPG) is safe, reported Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center investigators. This is the first larger scale study using a radiation-based direct drug delivery approach to treat and image DIPG.

DIPG is an aggressive cancer without any effective treatment—...

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reprogramming gut cells

Knocking out a single gene reprograms part of the large intestine to function like the nutrient-absorbing small intestine. In a preclinical study, Weill Cornell Medicine investigators showed that the technique reversed the malnutrition that results when most of the small intestine is removed. The successful demonstration suggests that a similar strategy could be used to treat short bowel syndrome, a life-threatening disorder that can occur when very little of the small intestine remains...

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line of vegetable oils in industrial setting

Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat “triple negative” breast cancer subtype, according to a preclinical study led by Weill Cornell Medicine investigators. The discovery could lead to new dietary and pharmaceutical strategies against breast and other cancers.

In the study...

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