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tuberculosis

Researchers at Weill Cornell Medicine have received a $17.4 million, five-year grant from the National Institute of Allergy and Infectious Diseases to discover new approaches to shorten tuberculosis (TB) treatment, potentially making it easier for patients to complete therapy. The researchers aim to shift TB drug development toward creating new drugs from the start to work in the combinations needed to cure TB. 

Though a course of antibiotics, when completed, can cure the infectious...

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UMAP with different colored dots

The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem cells to become shorter-lived white blood cells, according to a study by Weill Cornell Medicine investigators. Because the broad activity of interferon-alpha can induce significant side effects, developing new focused strategies based on these mechanistic findings could meet an important need in cancer therapy.

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two structural images

Metabotropic glutamate receptors, which are important but difficult drug targets, interact in surprisingly varied ways with their principal regulatory proteins, according to two new studies led by Weill Cornell Medicine investigators. The findings represent a big step forward in understanding these receptors and how they can be targeted effectively to potentially treat conditions such as epilepsy, depression, and anxiety disorders.

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HIV and neuron

Weill Cornell Medicine and Rutgers Health in New Brunswick have received a four-year, $3 million grant from the National Institute of Mental Health (NIMH) to build the infrastructure and resources that will accelerate discoveries about HIV-associated brain injury. The New York-New Jersey Center for Actionable NeuroHIV Biomarkers (NYJ-CAN-BIO) will provide the expertise, training and latest technologies needed to understand how HIV impacts the brain. This research center could uncover...

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photo of the legs of people wearing scrubs walking in a hallway

Contrary to some predictions, the use of artificial intelligence (AI) agents could lead to more, not fewer, health care professionals working in the United States, according to a new article by a physician and health policy researcher at Weill Cornell Medicine who surveyed economic theory and the history of technology in health care.

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histology of liver tissue

Obesity caused by disrupted stress-hormone rhythms is metabolically very different from obesity caused by a high-fat diet, according to a new preclinical study by Weill Cornell Medicine investigators. The researchers found in mice that glucocorticoid-rhythm disruption concentrates insulin resistance in skeletal muscle while preserving key insulin responses in fat tissue and liver. This allows fat tissue to continue storing lipids, while the liver remains largely protected from the fat...

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Dr. Geraldine McGinty

Dr. Geraldine McGinty, an esteemed academic healthcare leader and radiologist, has been appointed executive vice dean of Weill Cornell Medicine, effective Sept. 8.

In her new role, Dr. McGinty will serve as a vital strategic advisor to Dean Robert A. Harrington, exercise delegated authority on key matters and represent the institution internally and externally on topics central to Weill Cornell’s academic, clinical and professional life.

“In my nearly three years at Weill Cornell...

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stem cells tendon and ligaments

Researchers at Weill Cornell Medicine and Hospital for Special Surgery have discovered the stem cells—unspecialized cells that can develop into specific cell types—that give rise to the body’s tendons and ligaments, the tissues connecting muscles and bones. They also found that when these stem cells become hyperactive in the lower spine, they contribute to lumbar spinal stenosis. This condition, which impacts an estimated 103 million people worldwide, involves enlarged ligaments that can...

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Dr. Grinspan

Dr. Zachary Grinspan, associate professor of pediatrics and director of the Pediatric Epilepsy Program at Weill Cornell Medicine, has been awarded a four-year, $1.6 million CDC grant to undertake wide-reaching research aiming to produce a new, more detailed picture of childhood epilepsy.

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3D illustration of fungi Candida albicans

A commonly used systemic antifungal medication may help reduce symptoms in a subset of patients with inflammatory bowel disease (IBD) by restoring a healthier gut microbiome, according to a preliminary study by Weill Cornell Medicine investigators. 

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cartoon showing old and new approaches to blocking proteins

A team of Weill Cornell Medicine investigators has developed a computer model that will help scientists more efficiently develop protein-destroying therapies, a newer type of treatment that is particularly promising for cancer. The study was published July 13 in Nature Communications.

Most drugs use a small molecule to render disease-causing proteins harmless, but protein-degrader therapies aim to destroy the...

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tuberculosis bacteria

Tuberculosis bacteria released into the air from infected individuals dry out to form infectious particles that are second only to measles in contagiousness. Weill Cornell Medicine investigators have discovered specific mechanisms that enable the bacteria not only to survive drying but also to generate mutations linked to antibiotic resistance. This suggests that transmission involves more than the passive movement of bacteria between people and may be a period during which the pathogen...

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cartoon showing speedometer, on/off switch and scissors as ways bacteria can be manipulated

Weill Cornell Medicine investigators have developed a set of molecular tools to regulate the activity of specific genes in one of the most common classes of intestinal bacteria. The ability to genetically manipulate these microbes could lead to a better understanding of the role they play in human physiology and diseases.

In healthy individuals, species of Clostridia comprise half of the bacteria found in the gut. Many produce metabolites that are likely beneficial for human health and...

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Headshot of Dr. Dan Landau overlaying a picture of a building with flags

NEW YORK (Aug. 24, 2026)—Embracing the transformational potential of new molecular profiling and artificial-intelligence-based data processing technologies on clinical and scientific innovation, Weill Cornell Medicine has created a new research department, the Department of Systems and Computational Biomedicine. Dr. Dan Landau, an internationally recognized cancer researcher and...

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prostate cancer cell with cholesterol

Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.

The preclinical study, published Aug. 20 in Nature Metabolism, revealed that a compound called propionyl-CoA, produced by the breakdown of amino acids isoleucine and valine during normal energy metabolism...

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A group of students wearing white coats

Video of White Coat Ceremony Highlights 2026 | Weill Cornell Medicine

When Kiran Abraham-Aggarwal started his undergraduate studies at Cornell’s School of Industrial and Labor Relations (ILR), he assumed it would lead to a career in economic development or perhaps law, like many of his classmates. With an interest in advocacy and policy reform, these...

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A group of students pose for a photo

Video of White Coat Ceremony Highlights 2026 | Weill Cornell Medicine

Nina Almazar can trace her passion for healthcare to her untraditional upbringing, her family’s sacrifices—and her deep love for her grandmother.

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man standing in front of a whiteboard

A conceptual framework like the one engineers use for characterizing the transmission of sound and electrical signals can be useful in studying how olfaction—the sense of smell—is influenced by the air flow that carries odor molecules, according to a study led by investigators at Weill Cornell Medicine and the University of Colorado—Boulder. The new approach could lead to a better understanding of how olfaction works and better designs for artificial olfaction.

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Traumatic brain injury

Traumatic brain injury (TBI) in Pakistan is associated with a high risk of death and disability long after the initial injury, even in mild to moderate cases, according to two new studies in JAMA Network Open led by Weill Cornell Medicine researchers. While most TBIs occur in low- and middle-income countries due to road traffic accidents, long-term patient outcomes remain poorly understood.

To shed light on this critical issue, the researchers analyzed data from a trauma registry of...

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cells stained green and blue

Brain-resident immune cells that have reached an old-age state called “senescence” secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Cornell Medicine. The discovery sheds light on how aging impairs memory and cognition and makes the brain vulnerable to neurodegenerative disorders.

The researchers, whose ...

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