News & Events

Two Medicaid policies can interact to increase oncology clinical trial enrollment among Black and Hispanic patients, according to a new study by investigators at Weill Cornell Medicine, the University of Pennsylvania, and Medidata AI. Black and Hispanic patients are historically underrepresented in cancer clinical trials; equitable enrollment helps ensure the knowledge...

A simple blood test that measures the number of lymphocytes, a type of white blood cell in the body, may predict whether people who have relapsed multiple myeloma are going to respond well to CAR-T immunotherapy, according to new research from Weill Cornell Medicine, NewYork-Presbyterian, Columbia University and Icahn School of Medicine at Mount Sinai.

The...

A new preclinical model offers a unique platform for studying the Parkinson’s disease process and suggests a relatively easy method for detecting the disease in people, according to a study led by Weill Cornell Medicine researchers.

In the study, published July 23 in Nature Communications, the researchers showed that knocking out a key component involved in protein transportation in the light-sensing rod cells of mice...

Weill Cornell Medicine has received $4.2 million to study how the immune system in some people infected with HIV can keep the virus under control, which could lead to novel therapeutic strategies for thwarting or eliminating HIV. Dr. Brad Jones, associate professor of immunology in medicine in the Division of Infectious Diseases at Weill...

Researchers at Weill Cornell Medicine have used machine learning to define three subtypes of Parkinson’s disease based on the pace at which the disease progresses. In addition to having the potential to become an important diagnostic and prognostic tool, these subtypes are marked by distinct driver genes. If validated, these markers could also suggest ways the subtypes can be targeted with new and existing drugs.

The ...

Scientists from Weill Cornell Medicine and the Dana-Farber Cancer Institute in Boston have developed and tested new artificial intelligence (AI) tools tailored to digital pathology—a rapidly growing field that uses high-resolution digital images created from tissue samples to help diagnose disease and guide treatment.

Their paper, published July 9 in The Lancet Digital Health, demonstrates...

A new consortium co-led by Weill Cornell Medicine, has been awarded a five-year, $31 million grant from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases to accelerate the development of faster, more effective treatment regimens for tuberculosis (TB). Investigators at the University of California, San Francisco; Johns Hopkins Medicine; and Vanderbilt University Medical Center comprise the other co-leads.                

The Preclinical Design and...

Vaccinating mothers against respiratory syncytial virus (RSV) during late pregnancy to protect their newborns is not associated with an increased risk of preterm birth or other poor outcomes, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators. Infants are particularly vulnerable to the virus which can cause a serious lower respiratory illness.

The...

Endothelial cells with a distinct gene-expression signature play a key role in the development and repair of blood vessels throughout life, according to a new study by Weill Cornell Medicine investigators. 

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa—a vital tool in the search for an HIV cure that will benefit patients around the world.

The study, published July 2 in Nature Communications, helps fill a major gap in human immunodeficiency virus (HIV) research. Most HIV studies...

Researchers at Weill Cornell Medicine with an international team have used liver biopsies to identify cellular and molecular markers that can potentially be used to predict whether and when pancreatic cancer will spread to an individual’s liver or elsewhere, such as the lung.

The study, published on June 28 in Nature Medicine, proposes that information...

Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours—sometimes more than a day—in a reversible intermediate state, according to a discovery by researchers at Weill Cornell Medicine. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.

In...

Weill Cornell Medicine received a $1.5 million grant from the U.S. Department of Defense Prostate Cancer Research Program to develop new approaches for predicting the spread of cancer cells to the bone in men with prostate cancer, using tumor samples taken at early stages of the disease.

The American Cancer Society projects about 35,250 deaths from prostate cancer in the United States in 2024. “Metastases, especially to the bone, is the leading cause of death in men who have prostate...

The transition to menopause is marked by a progressively higher density of estrogen receptors (ER) on brain cells, a measure that remains elevated in women up to their mid-60s, according to a new brain imaging study led by researchers at Weill Cornell Medicine. In addition to revealing new evidence of the brain’s response to this major life change, the study pioneers the use of positron emission tomography (PET) imaging as a tool for studying estrogen activity in the brain, which hasn’t been...

“In this accelerator, we not only have our faculty explore their deep scientific questions but also help them expand their mindset to think of themselves as innovators and entrepreneurs,” said Loren Busby, director of BioVenture eLab, a part of Enterprise Innovation. She shared these remarks at the 2024 Business Plan Challenge pitch competition, which took place at Uris Auditorium on June 4.

The accelerator’s cohort of 24 participants...

An artificial intelligence-powered method for detecting tumor DNA in blood has shown unprecedented sensitivity in predicting cancer recurrence, in a study led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, the New York Genome Center (NYGC) and Memorial Sloan Kettering Cancer Center. The new technology has the potential to improve cancer care with the very early...

Interactions between two key structures within cells help establish the front-to-back “polarity” that is essential to cell migration, according to a new study by Weill Cornell Medicine researchers. These migrations occur in organ development, wound healing, cancer metastasis and many other processes, but how moving cells respond to environmental cues and set up internal structures that enable them to keep going in one direction has not been fully clear.

As the researchers...

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals—a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD). This family of disorders severely impacts the health and quality of life of more than 2 million people in the United States.

The immune system has many pathways to protect the body from...

Short-term space travel causes many of the same molecular and physiologic changes as long-term space missions, but most reverse within months of returning to Earth. Yet, those changes that are longer-lasting and distinct between crew members reveal new targets for aerospace medicine and can guide new missions, according to the results of a massive international research endeavor by investigators at Weill Cornell Medicine, SpaceX, and other organizations.

Dr....

Pregnancy and new motherhood transform a woman’s body as well as her life. While this is often a joyous time, it can sometime lead to mental health disorders, most often anxiety and depression. These conditions can be detrimental to the mother’s health and that of her child, but despite the high stakes, modern medicine often fails to address them. By teasing out the biological mechanisms underlying these pregnancy-related disorders, investigators at Weill Cornell Medicine are laying the...