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vein graft preparation

A new analysis shows that a combination of two anti-platelets drugs can benefit patients after the most common type of cardiac surgery — while also increasing the risk of potentially dangerous bleeding. This double-edged finding from Weill Cornell Medicine and NewYork-Presbyterian investigators suggests physicians should carefully weigh the use of these medications after this procedure. 

In an analysis...

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illustration of a person's head with a circadian clock

Disruption of the circadian clocks that keep the body and its cells entrained to the 24-hour day-night cycle plays a critical role in weight gain, according to a pair of studies by Weill Cornell Medicine investigators.  

One study, published June 27, in Cell Reports revealed that stress caused by chronically administering glucocorticoid stress hormones and disturbing the normal daily cycle of release...

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A man in suit and tie

NEW YORK (July 28, 2022)Dr. Jedd Wolchok, an internationally acclaimed medical oncologist whose innovations in immunotherapy have revolutionized melanoma treatment, has been recruited as the Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine, effective Sept. 12.

In his new role, Dr. Wolchok will lead an expansive,...

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illustration of a virtual office space

After experiencing a rapid expansion early in the COVID-19 pandemic, a new survey indicates that telemedicine is now widely viewed as an effective means for delivering care.

In results published online on June 15 in NEJM Catalyst Innovations in Care Delivery, a majority of respondents credited telemedicine with improving patient health, providing good quality care and increasing access for vulnerable populations....

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an illustration of a woman holding a baby

Vaccination against COVID-19 had no impact on the health of placentas in pregnant women, according to new research by pathologists at Weill Cornell Medicine and NewYork-Presbyterian. The findings, published June 27 as a research letter in the American Journal of Obstetrics & Gynecology, further emphasize the safety of vaccination during pregnancy for babies and pregnant women, the investigators note.

Most...

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a woman holding her baby

Antibodies that summon virus-engulfing white blood cells may play an important role in protecting infants from potentially serious congenital infection with human cytomegalovirus (HCMV), according to a study led by an investigator at Weill Cornell Medicine and NewYork-Presbyterian.

The study, which appeared June 28 in the Journal of Clinical Investigation, was the most comprehensive analysis of its kind to date in HCMV research....

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an illustration of fungi

Dr. Iliyan D. Iliev, an associate professor of immunology in medicine in the Division of Gastroenterology and Hepatology and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease at Weill Cornell Medicine, has been awarded a five-year, $1.25 million CRI Lloyd J. Old STAR (Scientists Taking Risks) Program grant from Cancer Research Institute (CRI).

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virtual reality scene next to brain imaging

Video of behaviorImage_combine15x

As mice navigate different rooms in virtual reality, the prefrontal neurons (top) communicate with those in the hippocampus (bottom) to conjure associated memories. Video courtesy of Nakul Yadav. From Yadav, N., Noble, C., Niemeyer, J.E. et al. Prefrontal feature representations drive memory recall. Nature...

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microscopic image

A protein called Zbtb46, expressed by specialized immune cells, has a major role in protecting the gastrointestinal tract from excessive inflammation, according to a study from researchers at Weill Cornell Medicine.

The finding, which appears July 13 in Nature, is a significant advance in the understanding of how the gut maintains health and regulates inflammation, which could lead to better strategies for treating...

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colocalization of extracellular DNA and CXCL4

Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according to a new study by researchers at Weill Cornell Medicine and Hospital for Special Surgery (HSS). The surprising discovery of this new activity for this well-studied class of immune signaling molecules could shed light on some types of immune...

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a woman posing for a photo

A Weill Cornell Medicine-led database of more than 15 million patients has received close to $8 million in renewed funding from the Patient-Centered Outcomes Research Institute (PCORI) to expand the database and its use for health research for the next three years.

The INSIGHT Clinical Research Network is a collection of de-identified...

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skull xray

Surgery can usually be avoided in children with a rare tumor of the skull, based on new research by investigators from Weill Cornell Medicine, NewYork-Presbyterian,...

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cars in traffic

Improvements in trauma care could save the lives of thousands of people injured in road traffic accidents in low- and middle-income countries annually, according to a study led by a Weill Cornell Medicine and NewYork-Presbyterian investigator. In particular, the analysis found that establishing complete trauma care programs accessible to 100 percent of road injury victims could save the lives of 200,000 people annually.

The...

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Cancer cells, malignant cells, scientific 3D illustration

A large clinical trial among people living with HIV has found that treating anal precancerous lesions cuts the risk of developing anal cancer by 57 percent compared with active monitoring with no treatment.

The ANCHOR study, published June 16 in the New England Journal of Medicine, was conducted at 25 clinical trial sites across the United States, including the Cornell HIV Clinical Trials Unit in the...

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image of a heart and EKG

A new onset of a rapid or irregular heartbeat that develops after surgery, often within a few days, is associated with an increased risk for hospitalization for heart failure among patients undergoing both cardiac and noncardiac surgery, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian investigators. The condition, called post-operative atrial fibrillation (POAF), may be a marker for early-stage heart failure and may potentially contribute to...

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closeup of doctor's hand writing in chart

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

In particular, the analysis, published June 28 in the Journal of Clinical Oncology, found that given the relatively low usage in some...

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illustration of DNA

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds. The genome is the complete set of genetic instructions, DNA or RNA, enabling an organism to function.

Using this method, the researchers demonstrated that cell function, including gene expression, may...

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Woman sitting at desk and reading

Dr. Sheila Nirenberg, the Nanette Laitman Professor of Neurology and Neuroscience and a professor of physiology and biophysics at Weill Cornell Medicine, has received the Barbara McClintock Women Innovator Award at the Inaugural Women Innovator Awards.

Launched by the Center for Technology Licensing (CTL) at Cornell University, the Inaugural Women Innovator Awards...

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three people sitting together taking a photo

Researchers have known for some time that maternal breast milk provides critical nutrients for newborns, and antibodies from mothers vaccinated against a specific disease-causing bacterium or virus can be transferred via breast milk to babies. Now a new preclinical study by Weill Cornell Medicine investigators shows that one specific set of antibodies that is induced naturally by gut beneficial bacteria can be transferred from mothers to infants through breast milk and help infants defend...

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model of lipid scrambling in cell membrane

A class of proteins known as TMEM16 scramblases permit rearrangement of lipids in the cell membrane chiefly by thinning the membrane, according to a new model by Weill Cornell Medicine investigators. The model, based on the highest-resolution images to date of a TMEM16 scramblase, challenges the prevailing theory of how these proteins play their fundamental role in biology and could lead to the first scramblase-targeted pharmaceuticals. 

Scramblase proteins reside in the outer...

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