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Cinthia Garcia was always passionate about science and medicine. The first in her family to complete post-secondary education, she earned a Bachelor of Science degree at Emmanuel College in Boston in 2018 and then became a laboratory manager at the UC San Diego School of Medicine. Still, she dreamed of a career as a physician-scientist, pursuing translational research with the potential to improve patient care. 

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heart bypass surgery

Women are at higher risk of death when undergoing heart bypass surgery than men. Researchers at Weill Cornell Medicine have determined that this disparity is mediated, to a large extent, by intraoperative anemia—a decrease in red blood cell concentration during surgery. The study, published on March 5, in the Journal of the American College of Cardiology, suggests that strategies for minimizing...

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magenta and cyan stained tissue

Treatment for rheumatoid arthritis (RA) has come a long way in recent years. In many cases, a battery of medications can now successfully stymy the inflammatory cells that cause swelling and pain when they infiltrate tissues around the joints. 

Yet for some reason, about 20% of patients with painful, visibly swollen joints consistently get no relief from multiple rounds of even the strongest of these anti-inflammatory drugs.

Surgical interventions intended to remove inflamed...

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drawing of heart with ecg line emanating from it

A clinical trial led by Weill Cornell Medicine investigators showed that a nasal spray that patients administer at home, without a physician, successfully and safely treated recurrent episodes of a condition that causes rapid abnormal heart rhythms. The study, published March 25 in the Journal of the American College of Cardiology, provides real-world evidence that a wide...

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mRNA isoforms

Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse and human brain. The atlas is an important new resource in understanding brain development, neuron specialization and other brain functions.

RNA transcripts that are copied from DNA sequences carry the instructions for building proteins and show which genes are active in a...

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image showing cells stained blue, tau aggregates in green and neuron cytoskeleton in red

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain—a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia. This new model has led to the identification of novel therapeutic targets that could potentially block tau spread.

The preclinical study, published April 5 in Cell, is a...

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bioengineered ear grafts

Using state-of-the-art tissue engineering techniques and a 3D printer, researchers at Weill Cornell Medicine and Cornell Engineering have assembled a replica of an adult human ear that looks and feels natural. The study, published March 16 in Acta Biomaterialia, offers the promise of grafts with well-defined anatomy and the correct biomechanical properties for those who are born with a congenital...

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cyan strands of DNA wrapped around green histone proteins

A team led by researchers at Weill Cornell Medicine has identified important drivers of the transformation of a type of blood cancer called follicular lymphoma from a slow-growing form to the aggressive form it takes in some patients.

The study, published March 7 in Cancer Cell, showed that while mutations affecting a gene-regulating complex called BAF can put the cancer on a dangerous trajectory, they also...

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Dr. Jedd Wolchok

A collaboration between Dr. Jedd Wolchok, the Meyer Director of the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine, and Dr. Yelena Janjigian, chief of the gastrointestinal oncology service at Memorial Sloan Kettering Cancer Center, is looking to transform the care of gastroesophageal cancer (GEC)...

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lung fibrosis

Researchers at Weill Cornell Medicine have discovered a protein that plays a critical role in clearing collagen from tissue and may be a therapeutic target to help prevent fibrosis, scar tissue that interferes with organ function. The paper, published on Feb. 20 in Nature Communications, provides clues that could lead to drug development for diseases like lung fibrosis which have no drug options currently.

Corresponding...

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Health Hackathon 2024

The 2024 Health Hackathon brought together 185 students with diverse backgrounds from Cornell and 26 other universities—in just 36 hours, they addressed critical safety challenges facing patients today.

The competition, held in person from March 8-10 and organized by Weill Cornell Medicine’s Clinical & Translational Science Center (CTSC) and...

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photo of a candle burning in the dark

Individuals with physical health concerns made up the largest and fastest growing of five subgroups of individuals who died by suicide in the United States over roughly twenty years, according to an analysis led by Weill Cornell Medicine in collaboration with Columbia University, UC Berkeley School of Public Health, the University of Hong Kong and University of Kentucky investigators.

The study, published...

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Dr. Samie Jaffrey

A team led by Dr. Samie Jaffrey, the Greenberg-Starr Professor of Pharmacology at Weill Cornell Medicine, has been awarded a three-year, $1.65 million grant for RNA research under a biotechnology-development program run by the U.S. National Science Foundation.

The competitive Molecular Foundations for Biotechnology program funds cutting...

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Photo of a hand holding a stethoscope on a man's arm with a blood pressure cuff

For younger Black patients living in rural parts of the Southeastern United States, peer coaching is more effective than traditional clinical care in controlling high blood pressure, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian. The investigators learned that for people under age 60 who have persistently uncontrolled hypertension, the benefits of working with a peer health coach were equivalent to what would be expected from taking a low...

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green and red labeled cells generated by imaging mass cytometry

Researchers at Weill Cornell Medicine have performed the most comprehensive analysis to date of cancer of the ureters or the urine-collection cavities in the kidney, known as upper tract urothelial carcinoma (UTUC).  The study, which compared the characteristics of primary and metastatic tumors, provides new insights into the biology of these aggressive cancers and potential ways to treat them.

In the...

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Group photo of celebrating students surrounded by balloons

Video of Match Day 2024 at Weill Cornell Medicine

Branden Sosa was halfway through his undergraduate degree at Hunter College when he had to take time off from school—his mother had been diagnosed with breast cancer. For a year and a half, he worked at Hospital for Special Surgery as an office manager to support his family.

“It was through that experience I grew to love orthopedics and research...

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newborn gut bacteria

Weill Cornell Medicine investigators discovered that unique bacteria colonize the gut shortly after birth and make the neurotransmitter serotonin to educate gut immune cells. This prevents allergic reactions to food and the bacteria themselves during early development.

The preclinical study, published in Science Immunology on Mar. 15, showed that bacteria abundant in the guts of newborns produce serotonin, which...

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nursing home care

Specialized nursing facility clinicians, or SNFists, may decrease the likelihood of nursing home residents experiencing stressful hospitalizations and improve the quality of life in their last days, according to researchers from Weill Cornell Medicine.

The study, published in JAMA Network Open on Mar. 15, examined how SNFists uniquely impacted the care of nursing home residents in their last 90 days,...

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Lewis Grossman

Rampant mistrust of medical science during the COVID-19 pandemic represents the rule, not the exception, of public perception of mainstream medicine over the last two centuries, said Lewis A. Grossman, a distinguished professor of law at American University’s Washington College of Law, in a lecture at Weill Cornell Medicine on March 13. 

“In October 2023, the Pew Research Center found that only 25 percent of U.S. adults say they have great...

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HIV care in Tanzania

Researchers at Weill Cornell Medicine have shown that three months of social worker follow-up support to people hospitalized with HIV in Tanzania had health benefits at low cost. The protocol shortened the time it took participants to attend an HIV clinic and to start on antiretroviral therapy after discharge.

However, the study published in JAMA on Mar. 6 found that the care benefits didn’t translate...

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