News & Events

Dr. Chenxu Zhu, an assistant professor of physiology and biophysics at Weill Cornell Medicine and a core faculty member of the New York Genome Center, has been awarded the National Institutes of Health Director’s New Innovator Award to fund an ambitious project to develop single-cell sequencing tools, known collectively as “multi-omics,” that...

Researchers at Weill Cornell Medicine have illuminated one of the important ways that cells respond to stress. The findings could also be relevant to Alzheimer’s, ALS and other diseases in which this mechanism may be abnormally active.

When stressed by heat, toxins or other potentially damaging factors, cells gather many of their messenger RNAs (mRNAs), molecules that carry the instructions for making proteins, into droplet-like compartments called stress granules. These granules...

Dr. Vanessa Bellat, an assistant professor of chemistry in radiology and an affiliate of the Molecular Imaging Innovations Institute (MI3) at Weill Cornell Medicine, has been awarded a $2 million, four-year R37 MERIT grant from the National Cancer Institute, part of the National Institutes of...

Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy—one that boosts T cells, and another that boosts dendritic cells—can control tumors in preclinical models of triple negative breast cancer, a cancer type that’s typically resistant to immunotherapy alone. Immunotherapy activates the body’s own immune system to fight cancer but isn’t effective for difficult-...

Weill Cornell Medicine has received a three-year, nearly $6 million grant to lead one of three national contraceptive research centers. The grant from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, part of the National Institutes of Health, will fund the Weill Cornell Medicine Contraception Development Research Center. Led by Drs. Jochen Buck and...

Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led by researchers at Weill Cornell Medicine.

Craniosynostosis arises from one of several possible gene mutations, and occurs in about one in 2,500 babies. By constricting brain growth, it can lead to abnormal brain development if not corrected surgically. In complex cases, multiple surgeries...

Weill Cornell Medicine has been awarded a five-year, $5 million grant from the United States Department of Health and Human Services through the Office of Population Affairs under the Teen Pregnancy Prevention Program to conduct a randomized trial testing whether a bilingual video game called “No Baby No (No Bebé No)” can increase the use of contraception among sexually active Black and Hispanic adolescents.

“Nine out of ten teens play video games. No Baby No empowers Black and...

The vertebral bones that form the spine are derived from a distinct type of stem cell that secretes a protein favoring tumor metastases, according to a study led by researchers at Weill Cornell Medicine. The discovery opens up a new line of research on spinal disorders, helps explain why solid tumors so often spread to the spine, and could lead to new orthopedic and cancer treatments.

In the study, published Sept. 13 in...

Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center have together been named a Rare Disease Center of Excellence by the National Organization for Rare Disorders (NORD). The designation adds the academic medical center to NORD’s collaborative network of 40 participating institutions that research and treat rare diseases.

“We are incredibly proud of...

As part of a National Institutes of Health initiative to improve maternal health and pregnancy outcomes nationwide, Weill Cornell Medicine and NewYork-Presbyterian will play a pivotal role as collaborators with Columbia University Irving Medical Center (CUIMC) as one of 10 nationwide IMPROVE (Implementing a Maternal Health and Pregnancy Outcomes Vision for Everyone)...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill Cornell Medicine and RMIT University in Australia have discovered that ion channels called BK channels have unique openings in their sides, which drug molecules may be able to access. The...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine. The discovery is a significant advance in cell biology, likely solves a long-standing mystery about an unusual feature of some ion channels and has implications for the development of drugs targeting these proteins and for drug delivery.

Ion channels are ubiquitous in the...

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

Results from the GLOW study, published July 31 in Nature Medicine, together...

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body’s immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators. The finding could help explain symptoms of prolonged inflammation and “long COVID” in people who have had the disease.

The research team, led by...

Watch the full Class of 2027 White Coat Ceremony on YouTube.

Nick Rosenfeld’s passion for medicine is profoundly personal, as is his desire for cultivating enduring relationships with patients...

A technique that enables scientists to record gene mutations and patterns of gene activity in individual cells has been extended to cover RNA splicing as well, in a study led by researchers at Weill Cornell Medicine, the New York Genome Center and the Princess Margaret Cancer Centre in Toronto. A better understanding of how aberrations in this process affects the development and behavior of...

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy. A new, very precise gene-editing tool created by Weill Cornell Medicine investigators will enable scientists to study the impact of these specific genetic changes in preclinical models rather than being limited to more broadly targeted tactics, such as deleting the entire gene.

The tool was...

Pregnant individuals who had a previous COVID-19 infection and received a full course of COVID-19 vaccination and a booster have the strongest immune protection from the disease – and pass that protection along to their unborn babies, according to a new study from Weill Cornell Medicine and The Rockefeller University investigators.

The researchers, whose study published Aug. 10 in Nature Communications, examined pregnant...

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

In the study, published Aug. 9 in the British Journal of Anaesthesia, the first-in-class drug conceptualized by lead author...