News & Events

Removing protected class regulation from Medicare prescription drug policies could greatly reduce the United States' prescription drug spending—this could have saved potentially $47 billion between 2011-2019, according to Weill Cornell Medicine researchers.

The study, published Oct. 7 in Health Affairs, aims to inform policymakers' debates about Medicare Part D covering the expense of all drugs in six "protected...

Dr. Alessandro Fichera, a prominent colorectal surgeon, has been named chief of the Division of Colorectal Surgery at NewYork-Presbyterian/Weill Cornell Medical Center and Weill Cornell Medicine, effective Oct. 14.

In his new role, Dr. Fichera leads a world-class team of colorectal surgeons that uses state-of-the-art technologies and innovative surgical techniques to provide...

NewYork-Presbyterian/Weill Cornell Medical Center and Weill Cornell Medicine have received the Emergency Medicine Wellness Center of Excellence Award from the American College of Emergency...

A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead to less invasiveness and weaker biological activity, according to a multicenter study conducted at Weill Cornell Medicine, NewYork-Presbyterian, Memorial Sloan Kettering Cancer Center and other institutions.

The...

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer’s disease (AD) together trigger a harmful inflammatory response in the brain’s immune cells, particularly in females, in a preclinical model.

The findings, published Sept. 30 in Neuron, emphasize the importance of considering sex differences in Alzheimer’s research – a step that could ultimately lead to...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study led by researchers at Weill Cornell Medicine. The findings suggest a potential strategy for enhancing the potency of anticancer immunotherapies.

In the...

A powerful new analytical tool offers a closer look at how tumor cells “shape-shift” to become more aggressive and untreatable, as shown in a study from researchers at Weill Cornell Medicine and the New York Genome Center.

A tumor cell shape-shifts by changing its cell type or state, thus altering its basic pattern of activity and perhaps even its appearance. This changeability or “plasticity” is a characteristic of cancer that leads to diverse...

A new preclinical model using CRISPR, an advanced technology that allows scientists to cut and edit genes, has given Weill Cornell Medicine researchers and their colleagues a deeper insight into how prostate cancer spreads or metastasizes.

In the study, published Sept. 23 in Cancer Discovery, scientists charted the complicated routes...

A multi-institutional clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators showed that a newer technique for collecting prostate biopsy samples reduced the risk of infection compared with traditional biopsy approaches.

The results of the study were published on Sept. 19 in JAMA Oncology.

The technique, called transperineal prostate biopsy, collects prostate tissue via a...

Individuals with compromised immunity and persistent COVID-19 infections can harbor drug-resistant variants of the SARS-CoV-2 virus, which have the potential to spread to the general population, a study by Weill Cornell Medicine, the College of Veterinary Medicine at Cornell University and the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID) found.

In the...

A new study helps explain why having ApoE4—the gene variant most closely linked to Alzheimer’s disease—increases the risk of neurodegeneration and white matter damage. Researchers at Weill Cornell Medicine discovered that immune cells in the brain called border-associated macrophages (BAMs) are a source of ApoE4 protein and contribute to damaging blood vessels and brain tissue.

Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to a new report from Weill Cornell Medicine and Dana-Farber Cancer Institute investigators and their colleagues.

The 10-year follow-up study, published Sept. 15 in the New England Journal of Medicine, will...

Researchers from Weill Cornell Medicine have used a cutting-edge model system to uncover the mechanism by which SARS-CoV-2, the virus that causes COVID-19, induces new cases of diabetes, and worsens complications in people who already have it. The team found that viral exposure activates immune cells that in turn destroy beta (β) cells, the pancreatic cells that produce insulin. The study was published Sept. 2...

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have created an intricate molecular map of the human body and its complex physiological processes based on the analysis of thousands of molecules measured in blood, urine and saliva samples from 391 volunteers. The data was integrated to create a powerful, interactive visual web-based tool called Connecting Omics (COmics) that can be used to investigate the complex...

Researchers at Weill Cornell Medicine have used artificial intelligence to identify drug targets based on mapping regulatory networks in patient tumors. The study, published Sept. 4 in Cell Systems, experimentally identified and validated four drug candidates for neuroendocrine, liver and renal cancers, which have a dismal prognosis with current therapeutic options.

This research offers a much-needed new way...

In a first-of-its-kind study, Weill Cornell Medicine researchers found that female physicians, primary care physicians, psychiatrists and physicians in non-rural areas delivered relatively higher proportions of visits via telehealth. This national analysis may provide key information for policymakers to consider as COVID-19 provisions for expanded Medicare telehealth coverage are set to expire at the end of this year.

By repeatedly scanning the brains of a small group of patients for a year and a half, Weill Cornell Medicine researchers have identified a distinct pattern of neuronal interactions that appears to predispose some people to developing depression.

Published Sept. 4 in Nature, the work highlights the potential of a new “deep scanning” approach to help predict a person’s...

Research at Weill Cornell Medicine suggests that childhood immunization against HIV could one day provide protection before risk of contracting this potentially fatal infection dramatically increases in adolescence.   

The study, published Aug. 30 in Science Immunology, demonstrated that a series of six vaccinations containing a modified protein from the surface of HIV particles stimulated initial steps of a potent...

A machine-learning tool created by Weill Cornell Medicine and Hospital for Special Surgery (HSS) investigators can help distinguish subtypes of rheumatoid arthritis (RA), which may help scientists find ways to improve care for the complex condition.

The study published Aug. 29 in Nature Communications shows that artificial intelligence and machine learning technologies can effectively and efficiently subtype...

An enzyme called PGK1 has an unexpectedly critical role in the production of chemical energy in brain cells, according to a preclinical study led by researchers at Weill Cornell Medicine. The investigators found that boosting its activity may help the brain resist the energy deficits that can lead to Parkinson’s disease.

The study, published Aug. 21 in Science Advances, presented evidence that PGK1 is a “rate-limiting”...