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illustration of a transparent body with an orange stomach and a red tumor in it

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

Results from the GLOW study, published July 31 in Nature Medicine, together...

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A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

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illustration of tree with black infestation spreading and orange fruit

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body’s immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators. The finding could help explain symptoms of prolonged inflammation and “long COVID” in people who have had the disease.

The research team, led by...

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Students wearing short white coats sitting in rows of seats in an auditorium.

Video of Class of 2027 White Coat Ceremony Highlights | Weill Cornell Medicine

Watch the full Class of 2027 White Coat Ceremony on YouTube.

Nick Rosenfeld’s passion for medicine is profoundly personal, as is his desire for cultivating enduring relationships with patients...

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blood cells stained with Wright-Giemsa stain

A technique that enables scientists to record gene mutations and patterns of gene activity in individual cells has been extended to cover RNA splicing as well, in a study led by researchers at Weill Cornell Medicine, the New York Genome Center and the Princess Margaret Cancer Centre in Toronto. A better understanding of how aberrations in this process affects the development and behavior of...

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Organoid labeled with fluorescent green and red markers

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy. A new, very precise gene-editing tool created by Weill Cornell Medicine investigators will enable scientists to study the impact of these specific genetic changes in preclinical models rather than being limited to more broadly targeted tactics, such as deleting the entire gene.

The tool was...

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Pregnant woman wearing a pink dress with her hands over her belly

Pregnant individuals who had a previous COVID-19 infection and received a full course of COVID-19 vaccination and a booster have the strongest immune protection from the disease – and pass that protection along to their unborn babies, according to a new study from Weill Cornell Medicine and The Rockefeller University investigators.

The researchers, whose study published Aug. 10 in Nature Communications, examined pregnant...

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Cartoon illustration showing an anchor tied to a wire, located to the left of several squiggly lines colored in green, blue, yellow and pink.

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

In the study, published Aug. 9 in the British Journal of Anaesthesia, the first-in-class drug conceptualized by lead author...

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HCV test

While there are highly effective treatments for the hepatitis C virus (HCV), only 1 in 5 Medicaid enrollees diagnosed with HCV started treatment, according to a retrospective study led by researchers at Weill Cornell Medicine and Cornell University’s Ithaca campus. The findings revealed that treatment uptake rates were even lower among people under 30, women, Hispanic and Asian individuals, as well as people who inject drugs. The research underscores the urgent need for public health and...

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man in suit jacket sitting at lab hood

Dr. Gregory F. Sonnenberg, The Henry R. Erle, M.D.-Roberts Family Associate Professor of Medicine and head of basic research in Gastroenterology and Hepatology at Weill Cornell Medicine, has been awarded a $3.26 million, five-year MERIT grant from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to investigate the underlying mechanisms of inflammatory...

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Team of surgeons

A multi-institutional team of scientists led by Dr. Mario Gaudino, the Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery and assistant dean for clinical trials at Weill Cornell Medicine, has been approved for a nearly $30 million funding award from the Patient-Centered Outcomes Research Institute (PCORI). The award will fund the first study among women and Black and Hispanic patients comparing the effectiveness of...

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Pharmacist selecting pills from an open shelf full of boxes

The availability of generic antiviral drugs to manage chronic hepatitis B resulted in significant savings to Medicare, despite an increase in prescriptions, according to an analysis by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The findings were published July 8 in Gastroenterology.

About 1.6 million people in the United States live with chronic hepatitis B. There is no cure...

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ventilator monitor reading 'standby' in foreground with hospital bed in background

During the COVID-19 pandemic, many U.S. hospitals had overcapacity intensive care units (ICU) while other area hospitals had open ICU beds available, a phenomenon known as “load imbalance.” The hospitals most likely to be overloaded in imbalanced regions served a higher number of Black patients and more patients enrolled in Medicaid, according to a new study conducted by Weill Cornell Medicine investigators.

In the...

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female doctor in scrubs and mask looking through window blinds

Using an innovative method for measuring doctor turnover, Weill Cornell Medicine researchers determined that between 2010 and 2018, the annual rate at which physicians left their practices increased by 43 percent, from 5.3 percent to 7.6 percent a year.  The causes of this trend are not known, but warrant further investigation, according to the researchers.

The study, published July 11 in the Annals of Internal Medicine, also found that...

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line drawing of a woman holding a baby

Breastfeeding and pumping are widely recognized as beneficial for both mother and child. However, due to ability of both to burn calories, some women may excessively breastfeed and pump as a method of weight control, according to a new paper by investigators at Weill Cornell Medicine and Yale School of Medicine. Women with a history of an eating disorder or a current eating disorder are likely at particular risk, the investigators note. They posit that breastfeeding and pumping in this way...

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photo of woman grasping her knee and leg

State laws allowing medical cannabis use did not reduce prescriptions for opioids or other therapies for chronic, non-cancer pain, according to a policy analysis by Weill Cornell Medicine investigators.

Dr. Beth McGinty, chief of the Division of Health Policy and Economics at Weill Cornell Medicine, used a study design that emulates a clinical trial to analyze the effects of medical cannabis laws on...

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image of cancer cells dividing

An atlas that catalogues gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

The researchers, who published their work June 19 in Nature Metabolism, created the Cancer Atlas of Metabolic Profiles (CAMP) by combining new and existing...

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illustration of diverse group of people

Weill Cornell Medicine and Columbia University have been awarded a $9.8 million, five-year grant from the National Cancer Institute (NCI), part of the National Institutes of Health, to help combat cancer disparities fueled by persistent poverty.

The competitive award will engage faculty members from Weill Cornell Medicine,...

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photo of masked person administering vaccine to another masked person

A model for optimizing the dispensing of vaccines during pandemics that uses a new measure of success for such efforts has been developed by researchers at Weill Cornell Medicine, the Ithaca campus of Cornell University, Singapore University of Technology and Design and San Jose State University in California. The new model expands the concept of vaccine coverage to include 'vaccinated person-days' (VPDs), which prioritizes both the number of people vaccinated and the speed of getting shots...

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a group of medical professionals in a room having a meeting

Today, Weill Cornell Imaging at NewYork-Presbyterian’s radiology consultation service is a much-used resource among Weill Cornell Medicine physicians. But little more than a decade ago, this program—in which imaging experts provide real-time imaging ordering assistance and oncology-related consultations—was just a back-of-the-envelope idea that Dr. Keith Hentel (M.D. ’98...

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