News & Events

Convalescent plasma did not reduce the risk of intubation or death for hospitalized COVID-19 patients in a large, international clinical trial conducted by Weill Cornell Medicine and NewYork-Presbyterian investigators in collaboration with lead investigators at McMaster University.

The study, published Sept. 9 in Nature Medicine, also revealed that patients who received convalescent plasma experienced...

The master regulator behind the development of antibody-producing cells has been identified in a study by investigators at Weill Cornell Medicine. The findings provide new insight into the inner workings of the immune system and may help understand how tissues develop and how certain cancers arise.

The study, published Sept. 23 in Nature Immunology, combined computational analyses with advanced molecular biology and...

Turning off a defense mechanism that protects colorectal cancer tumors from being discovered by immune cells could be a possible strategy for treating the disease, according to a new study by Weill Cornell Medicine investigators. Because immunotherapy reactivates immune cells near a tumor, but fails when those cells aren’t present in significant numbers, the new approach could potentially complement this type of treatment or work on its own.

The...

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

Stroke patients received clot-busting medication more quickly,and had better recoveries, when treated by an ambulance-basedmobile stroke unit (MSU) compared with standard emergency room (EMS) care, according to a study from researchers at UTHealth Houston, Memorial Hermann-Texas Medical Center, Weill Cornell Medicine, NewYork-Presbyterian, and five other medical centers across the United States.

A team co-led by scientists at Weill Cornell Medicine has revealed in detail how the most common primary eye cancer in adults, uveal melanoma (UM), can progress from a slow-growing, “indolent” state to a lethal metastasizing state. The discovery is a significant advance in fundamental cancer research that also suggests new strategies for treatment.

The scientists, whose study is published Sept. 13 in Nature Communications...

Tuberculosis (TB) is a wily old killer, one of the deadliest infectious diseases in history and one of the few that naturally infects only humans. Researchers at Weill Cornell Medicine have been pursuing treatments for tuberculosis caused by Mycobacterium tuberculosis (Mtb) since the 1950s, and the program continues to excel at explaining TB’s mysteries and pushing toward more effective therapies.

Currently, Weill Cornell Medicine investigators are...

Children with infantile spasms, a rare form of epileptic seizures, should be treated with one of three recommended therapies and the use of non-standard therapies should be strongly discouraged, according to a study of their effectiveness by a Weill Cornell Medicine and NewYork-Presbyterian investigator and collaborating colleagues in the Pediatric Epilepsy Research Consortium. Early treatment with an effective therapy is important for improving neurodevelopmental outcomes and, for some...

As a child, Noelle Desir, 23, suffered from severe eczema. She and her family tried everything to bring the skin condition under control, but without insurance, all they could do was visit the emergency room when she had a flare-up. Finally at age 12, her father, an immigrant from Haiti, secured...

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

The researchers, who published their findings August 17...

Researchers at Weill Cornell Medicine have shown that they can record the high-speed motions of proteins while correlating their motion to function. The feat should allow scientists to study proteins in greater detail than ever before, and in principle enables the development of drugs that work better by hitting their protein targets much more effectively.

The researchers, in a study published July 16 in Nature...

The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine. The discovery could lead to new methods for classifying and treating patients with this disease.

The researchers, who published their findings August 11 in Cell, found that in a number of lupus patients, maturing red blood cells fail to...

Dr. Geraldine McGinty, an esteemed clinical operations strategist, administrator and radiologist, has been appointed senior associate dean for clinical affairs at Weill Cornell Medicine, effective Sept. 1.

In her new role, Dr. McGinty will provide Dean Augustine M.K. Choi with strategic counsel and work to realize his vision for the institution’s clinical...

Researchers at Weill Cornell Medicine have identified a population of neurons that drive animal brains to initiate actions without prompting from an external stimulus such as food or prey. The preclinical finding is a significant step towards solving what has been one of the big unanswered questions in neuroscience.

The study, published July 6 in Nature Communications, used advanced experimental techniques to monitor the...

Treatment with a ready-made preparation of human immune cells helps prevent infections in people whose immune systems are temporarily weakened by leukemia treatment, according to a phase 2 clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. Infections are a significant problem in patients undergoing chemotherapy for cancer.

The cell preparation, known as romyelocel-L, consists of immature, human-derived immune cells that work to replenish white blood...

The genetic changes that underlie an especially lethal type of prostate cancer have been revealed in a new study by investigators at Weill Cornell Medicine. Learning more about what causes this type of cancer, called neuroendocrine prostate cancer (NEPC), could lead to new approaches for treating it.

Most early-stage prostate cancers require male hormones (androgens) like testosterone to grow. However, as they advance, they may evolve into castration-resistant prostate cancer (CRPC), a...

The structure and function of an important protein that transports essential omega-3 fatty acid molecules from the bloodstream into the brain has been determined by a team led by scientists at Columbia University Vagelos College of Physicians and Surgeons, Weill Cornell Medicine, and Duke-NUS Medical School. The findings illuminate a crucial aspect of brain health and development, and open the...

Click on the image to view a video about the paper.

Scientists at Weill Cornell Medicine have...

Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The study findings may have implications for developing better risk assessment tools for TNBC in African American women and for understanding why they have poorer TNBC outcomes.

In a...

A new understanding of the interaction of two proteins and their role in fat burning and storage may one day have implications for the treatment of obesity and associated diseases such as diabetes and cancer, according to Weill Cornell Medicine investigators.

Their preclinical research, published May 17 in Nature Communications, explores how the proteins p62 and NBR1 influence thermogenesis, or fat burning to produce body...