News & Events

Children with infantile spasms, a rare form of epileptic seizures, should be treated with one of three recommended therapies and the use of non-standard therapies should be strongly discouraged, according to a study of their effectiveness by a Weill Cornell Medicine and NewYork-Presbyterian investigator and collaborating colleagues in the Pediatric Epilepsy Research Consortium. Early treatment with an effective therapy is important for improving neurodevelopmental outcomes and, for some...

As a child, Noelle Desir, 23, suffered from severe eczema. She and her family tried everything to bring the skin condition under control, but without insurance, all they could do was visit the emergency room when she had a flare-up. Finally at age 12, her father, an immigrant from Haiti, secured...

An immune cell subset called innate lymphoid cells (ILC3s) protects against colorectal cancer, in part by helping to maintain a healthy dialogue between the immune system and gut microbes, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The finding opens the door to new strategies for treating this type of cancer.

The researchers, who published their findings August 17...

Researchers at Weill Cornell Medicine have shown that they can record the high-speed motions of proteins while correlating their motion to function. The feat should allow scientists to study proteins in greater detail than ever before, and in principle enables the development of drugs that work better by hitting their protein targets much more effectively.

The researchers, in a study published July 16 in Nature...

The autoimmune disease lupus may be triggered by a defective process in the development of red blood cells (RBCs), according to a study led by researchers at Weill Cornell Medicine. The discovery could lead to new methods for classifying and treating patients with this disease.

The researchers, who published their findings August 11 in Cell, found that in a number of lupus patients, maturing red blood cells fail to...

Dr. Geraldine McGinty, an esteemed clinical operations strategist, administrator and radiologist, has been appointed senior associate dean for clinical affairs at Weill Cornell Medicine, effective Sept. 1.

In her new role, Dr. McGinty will provide Dean Augustine M.K. Choi with strategic counsel and work to realize his vision for the institution’s clinical...

Researchers at Weill Cornell Medicine have identified a population of neurons that drive animal brains to initiate actions without prompting from an external stimulus such as food or prey. The preclinical finding is a significant step towards solving what has been one of the big unanswered questions in neuroscience.

The study, published July 6 in Nature Communications, used advanced experimental techniques to monitor the...

Treatment with a ready-made preparation of human immune cells helps prevent infections in people whose immune systems are temporarily weakened by leukemia treatment, according to a phase 2 clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. Infections are a significant problem in patients undergoing chemotherapy for cancer.

The cell preparation, known as romyelocel-L, consists of immature, human-derived immune cells that work to replenish white blood...

The genetic changes that underlie an especially lethal type of prostate cancer have been revealed in a new study by investigators at Weill Cornell Medicine. Learning more about what causes this type of cancer, called neuroendocrine prostate cancer (NEPC), could lead to new approaches for treating it.

Most early-stage prostate cancers require male hormones (androgens) like testosterone to grow. However, as they advance, they may evolve into castration-resistant prostate cancer (CRPC), a...

The structure and function of an important protein that transports essential omega-3 fatty acid molecules from the bloodstream into the brain has been determined by a team led by scientists at Columbia University Vagelos College of Physicians and Surgeons, Weill Cornell Medicine, and Duke-NUS Medical School. The findings illuminate a crucial aspect of brain health and development, and open the...

Click on the image to view a video about the paper.

Scientists at Weill Cornell Medicine have...

Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The study findings may have implications for developing better risk assessment tools for TNBC in African American women and for understanding why they have poorer TNBC outcomes.

In a...

A new understanding of the interaction of two proteins and their role in fat burning and storage may one day have implications for the treatment of obesity and associated diseases such as diabetes and cancer, according to Weill Cornell Medicine investigators.

Their preclinical research, published May 17 in Nature Communications, explores how the proteins p62 and NBR1 influence thermogenesis, or fat burning to produce body...

A team led by researchers at Weill Cornell Medicine and Children’s National Hospital has developed a unique pre-clinical model that enables the study of long-term HIV infection, and the testing of new therapies aimed at curing the disease.

Ordinary mice cannot be infected with HIV, so previous HIV mouse models have used mice that carry human stem cells or CD4 T cells, a type of immune cell that can be infected with HIV. But these models tend to have limited utility because the human...

Adding antibiotics to usual care does not improve outcomes for people with the lung disease idiopathic pulmonary fibrosis (IPF), according to the findings from a multi-center, phase 3 clinical trial sponsored by Weill Cornell Medicine.

Importantly, the investigators note that although the trial had negative findings, the novel way it was designed and conducted could pave the way for future studies that are less expensive and easier to conduct. The...

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease. Now a team led by researchers at Weill Cornell Medicine, NewYork-Presbyterian and the New York Genome Center (NYGC) has developed a machine learning technique for detecting other modifications to DNA that have a similar effect.

The...

Weill Cornell Medicine’s commitment to diversity and inclusion spans all parts of its mission, but starts with education. From its pipeline programs to an increasingly engaged student population, the institution strives to build an inclusive community where the next generation of diverse physicians and scientists are equipped to address issues of health equity and advocate for patients from all backgrounds.

A Pipeline to Medicine and Community Care

Weill Cornell Medicine’s vast...

Patients with gynecologic cancers who have Medicaid coverage are more likely to feel increased financial distress, anxiety about their cancer and increased general anxiety during the pandemic if their annual income is less than $40,000, according to a new study from Weill Cornell Medicine investigators.

The study’s findings, published April 26 in Cancer, suggest that physicians should ask these women more about the challenges they face in completing their treatments and link them with...

The heart damage seen in many severely ill COVID-19 patients results in part from infection-activated immune cells called macrophages, which infiltrate the heart and secrete cell-damaging chemicals, according to a study co-led by researchers at Weill Cornell Medicine, NewYork-Presbyterian, Icahn School of Medicine at Mount Sinai and Columbia University Irving Medical Center. The research identifies new...

Dr. Jeffrey Laurence, a professor of medicine in the Division of Hematology and Medical Oncology at Weill Cornell Medicine and a hematology and oncology specialist at NewYork-Presbyterian/Weill Cornell Medical Center, co-authored a now-widely cited...