Histone H1 (fragment shown here in gray) binds and condenses DNA to repress gene activity. Mutations in histone H1 (highlighted in red) have been identified at high frequency in many hematological malignancies.
A gene therapy developed by Weill Cornell Medicine and NewYork-Presbyterian investigators helped slow progression of a rare and fatal genetic disorder in children called late infantile Batten...
Microscopic image of Ustilago maydis cells. The fluorescent image on the right shows that damaged telomeres (green dots) can recruit a DNA repair protein (red). Image courtesy of the Lue lab.
Patient mistrust of the healthcare system, which has come under new focus during the COVID-19 pandemic, is partly the result of an increasingly consumer-oriented healthcare system, according to a new commentary by a Weill Cornell Medicine investigator.
"Trust is the glue that holds all of healthcare together,” said lead author Dr. Dhruv Khullar, an assistant...
Hospitals in the U.S. began receiving the first COVID-19 vaccine on December 14 and vaccinating healthcare workers, in the first step of the biggest vaccination campaign in U.S. history. On December 11, the ...
Coronary artery plaque 3d illustration. Credit: Shutterstock
The risk of dying seven years after coronary artery bypass surgery was significantly lower in men receiving multiple bypass grafts rather than single grafts, but there was no apparent...
Participants in Eighth Annual Appel Alzheimer's Disease Research Institute Symposium. Top, left to right: Dr. Matthew Fink, Dr. Bruce Miller, Dr. Anna Orr. Bottom, left to right: Dr. Jonathan Kipnis, Dr. Manu Sharma, Dr. Li Gan.
Human pluripotent stem cell-derived alveolar organoid xenograft. Red: Pro-SP-B (an Alveolar Type 2 cell marker) and Green: ACE2 (a receptor of SARS-CoV-2). Image courtesy of Dr. Shuibing Chen.
Human organoids, tiny organ-like structures grown in...
Construction site of tents for overflow capacity for hospitals. Credit: Shutterstock
Researchers from Weill Cornell Medicine, Cornell University and San Jose State University have identified six free planning models for estimating hospital...
Image of a colon tumor in mice. Cancer-associated fibroblasts (red) help the tumor grow more aggressively and help block the immune system response against it.
Molecular changes in cells called fibroblasts, which help provide support for...
The COVID-19 pandemic will potentially lead to greater disparities in cancer care and outcomes among Black and Hispanic New Yorkers, according to a viewpoint article published in JAMA Oncology on Aug. 13 by Weill Cornell Medicine and NewYork-Presbyterian investigators. The authors write that higher rates of SARS-CoV-2 infection among Blacks and Hispanics will lead to delays...
A study by investigators at Weill Cornell Medicine and NewYork-Presbyterian aims to answer one of COVID-19’s biggest mysteries: why do some people become severely ill, while others have no symptoms? The multidisciplinary team will seek to identify underlying genetic and immune factors that contribute to these varying outcomes to help guide the development of precision prevention and treatment efforts.
With the need for wide scale COVID-19 testing to allow societies reopen safely, a group from Weill Cornell Medicine and other academic medical centers and research organizations have announced the launch of a global competition for low-cost, high-quality and scalable COVID-19 tests, called the COVID-19 XPRIZE, in a ...
The amount of SARS-CoV-2 virus, or “viral load,” in cancer patients and in the general inpatient population upon hospital admission may predict their risk of dying of the infection, according to a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The findings provide new insights into the relationship between viral load and the risk of severe illness in both populations and may help guide treatment decisions.
