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structure of ion channel with cartoon of lipid binding below

The mechanism by which fat-related molecules called lipids regulate pacemaker ion channel proteins, which help control the heart rhythm, has been revealed in a study from researchers at Weill Cornell Medicine.

In the study, published Nov. 9 in Nature Structural & Molecular Biology, the researchers used advanced methods including cryogenic electron microscopy (cryo-EM) to show in high-resolution detail how certain...

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pill bottles

Weill Cornell Medicine has been awarded a five-year, $8.1 million grant from the National Institutes of Health (NIH) to support economic analysis, simulation modeling and other research approaches to help stem the national opioid epidemic.    

“We’ve continued to witness the very disturbing increase in opioid overdoses over the last seven years, fueled by more fentanyl in the drug supply,” said principal investigator...

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COVID-19 patients placed on ventilators can take a long time to regain consciousness. New research from Weill Cornell Medicine, NewYork-Presbyterian, MIT, and Massachusetts General Hospital is now illustrating that these delays may serve a purpose: protecting the brain from oxygen deprivation.

The existence of such a brain-preserving state could explain why some patients wake up days or even weeks after they stop receiving ventilation, and it suggests that physicians should take these...

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NEW YORK (Nov. 3, 2022)Dr. Pranita Tamma, a physician-scientist whose research focuses on identifying mechanisms of drug resistance and optimizing the use of antibiotics to treat infections in children, has been awarded the seventh annual Gale and Ira Drukier Prize in Children’s Health Research, Weill Cornell Medicine announced today.

The Drukier Prize honors an...

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goblet cells

A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other parts of the body, according to a preclinical study from researchers in the Friedman Center for Nutrition and Inflammation and Jill Roberts Institute for Inflammatory Bowel Disease at Weill Cornell Medicine and in the Boyce Thompson Institute on Cornell’s Ithaca campus.

...

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ILC2 and goblet cells in intestines

Innate lymphoid cells are a recently discovered family of white blood cells that reside in the skin, gastrointestinal tract, airways and other barrier tissues of the body. Group 2 innate lymphoid cells (ILC2s) have an essential role in protecting these tissues from parasitic infections as well as damage associated with allergic inflammation and asthma, according to a new study led by Weill Cornell Medicine researchers.

The finding resolves a controversy about the possible redundancy of...

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doctors in a hospital

New York, NY (November 1, 2022) – NewYork-Presbyterian is expanding its renowned heart transplant program, one of the largest and most experienced heart transplant programs in the nation, and increasing access to its world-class heart failure care.

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mass cytometry image of a healthy lung

Weill Cornell Medicine researchers have developed a computational method to map the architecture of human tissues in unprecedented detail. Their approach promises to accelerate studies on organ-scale cellular interactions and could enable powerful new diagnostic strategies for a wide range of diseases.

The method, published Oct. 31 in Nature Methods, grew out of the scientists’ frustration...

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Dr. Brenna Farmer has been named chief of the Department of Emergency Medicine at NewYork-Presbyterian Brooklyn Methodist Hospital, effective Oct. 11. Dr. Farmer, who is also an associate professor of clinical emergency medicine at Weill Cornell Medicine, most recently served as vice chief of clinical services in the Department of Emergency Medicine at NewYork-Presbyterian Brooklyn Hospital.

“We are delighted to welcome Dr. Farmer into...

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image of Endovascular Aortic Aneurysm Repair

By linking a national vascular registry with medical data records in Medicare claims for patients who underwent endovascular abdominal aortic aneurysm repair, a team of researchers from across the country was able to identify which devices posed the most risk for reintervention.

The study, published Oct. 25 in BMJ, is the first to use linked registry claims data for long-term device-specific surveillance after surgery for...

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Dr. Prigerson

Dr. Holly G. Prigerson, the Irving Sherwood Wright Professor in Geriatrics and co-director of the Center for Research on End-of-Life Care at Weill Cornell Medicine, has been awarded a National Cancer Institute Outstanding Investigator Award to study psychosocial influences on, and outcomes of, end-stage cancer care.

Funded by the NIH, the award supports accomplished...

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A woman scientist in the lab

A multi-institutional team of scientists, led by researchers at Weill Cornell Medicine’s Gale and Ira Drukier Institute for Children's Health, have received a five-year $8.297 grant to continue funding a Center for Lupus Research. The grant, awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health, will allow researchers to...

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Endothelial cells—the cells that line blood vessels—grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study by Weill Cornell Medicine investigators found.

A growing body of evidence suggests that genetic mutations are not enough to cause cancer; tumor cells also need the right environment to grow. The new...

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microscopic image

Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a study from researchers at Weill Cornell Medicine.

The researchers, whose report appears Oct. 14 in Cell, found in a preclinical model that pain-sensing neurons in the gut secrete a molecule called substance P, which appears to protect against gut...

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immunofluorescent image of Zika infecting brain organoids

A mitochondrial gene plays a crucial role in genetic susceptibility to Zika, Dengue, and SARS-CoV-2 infections, a study by Weill Cornell Medicine investigators showed.

The study, published Oct. 6 in Cell Stem Cell, provides proof of principle that cell-based genome-wide association studies (GWAS) could be a valuable tool for studying genetic susceptibility to infections and other diseases. Genome-wide...

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Two genes working in concert sustain the integrity of healthy blood vessels, Weill Cornell Medicine investigators discovered in new research. The findings could lead to new approaches treating cardiovascular disease or other inflammatory conditions.

The preclinical study, published Oct. 6 in Nature Cardiovascular Research, shows that the transcription factors ERG and FLI1 work together to shepherd the blood...

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a woman holding her baby

A cellular process known as autophagy that helps rid cells of debris may be impaired in pregnant women who go on to develop post-partum depression (PPD), according to new research from Weill Cornell Medicine, Johns Hopkins University School of Medicine and UVA Health investigators.

“Our research indicates that autophagy may be dampened in pregnant women who...

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researcher examining psychedelic mushrooms

The psychedelic drugs LSD and psilocybin activate serotonin receptors on brain cells in a way that reduces the energy needed for the brain to switch between different activity states, according to a study led by Weill Cornell Medicine researchers.

The study, which appeared Oct. 3 in Nature Communications, offers insight into the mechanism of these drugs’ effects—effects that many hope can someday be harnessed...

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Stock image of the Brooklyn Bridge

Dr. Asim Shahid, a leading pediatric neurologist who specializes in the treatment of childhood epilepsy, has been named chief of the Division of Pediatric Neurology at NewYork-Presbyterian Brooklyn Methodist Hospital. Dr. Shahid was also recruited to Weill Cornell Medicine as an interim assistant professor of clinical pediatrics.

In his new role, Dr. Shahid will expand and enhance NewYork-Presbyterian Brooklyn Methodist Hospital’s world-class pediatric neurology and epilepsy services,...

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an elderly woman getting medical care

For the fifth consecutive year, NewYork Quality Care, the accountable care organization (ACO) of NewYork-Presbyterian, Columbia University Irving Medical Center and Weill Cornell Medicine, has earned shared savings in the Centers for Medicare & Medicaid Services (CMS) Medicare Shared Savings Program. In 2021, NewYork Quality Care saved Medicare $26,335,014 while providing high quality care for more than 35...

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