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A Weill Cornell Medicine-led database of more than 15 million patients has received close to $8 million in renewed funding from the Patient-Centered Outcomes Research Institute (PCORI) to expand the database and its use for health research for the next three years.

The INSIGHT Clinical Research Network is a collection of de-identified...

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skull xray

Surgery can usually be avoided in children with a rare tumor of the skull, based on new research by investigators from Weill Cornell Medicine, NewYork-Presbyterian,...

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cars in traffic

Improvements in trauma care could save the lives of thousands of people injured in road traffic accidents in low- and middle-income countries annually, according to a study led by a Weill Cornell Medicine and NewYork-Presbyterian investigator. In particular, the analysis found that establishing complete trauma care programs accessible to 100 percent of road injury victims could save the lives of 200,000 people annually.

The...

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Cancer cells, malignant cells, scientific 3D illustration

A large clinical trial among people living with HIV has found that treating anal precancerous lesions cuts the risk of developing anal cancer by 57 percent compared with active monitoring with no treatment.

The ANCHOR study, published June 16 in the New England Journal of Medicine, was conducted at 25 clinical trial sites across the United States, including the Cornell HIV Clinical Trials Unit in the...

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image of a heart and EKG

A new onset of a rapid or irregular heartbeat that develops after surgery, often within a few days, is associated with an increased risk for hospitalization for heart failure among patients undergoing both cardiac and noncardiac surgery, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian investigators. The condition, called post-operative atrial fibrillation (POAF), may be a marker for early-stage heart failure and may potentially contribute to...

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closeup of doctor's hand writing in chart

There is considerable variation in the management of mantle cell lymphoma across different clinical settings, and some strategies do not always conform with what might be expected, according to an analysis by investigators from Weill Cornell Medicine and other leading health institutions.

In particular, the analysis, published June 28 in the Journal of Clinical Oncology, found that given the relatively low usage in some...

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illustration of DNA

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, or how the genome folds. The genome is the complete set of genetic instructions, DNA or RNA, enabling an organism to function.

Using this method, the researchers demonstrated that cell function, including gene expression, may...

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Woman sitting at desk and reading

Dr. Sheila Nirenberg, the Nanette Laitman Professor of Neurology and Neuroscience and a professor of physiology and biophysics at Weill Cornell Medicine, has received the Barbara McClintock Women Innovator Award at the Inaugural Women Innovator Awards.

Launched by the Center for Technology Licensing (CTL) at Cornell University, the Inaugural Women Innovator Awards...

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three people sitting together taking a photo

Researchers have known for some time that maternal breast milk provides critical nutrients for newborns, and antibodies from mothers vaccinated against a specific disease-causing bacterium or virus can be transferred via breast milk to babies. Now a new preclinical study by Weill Cornell Medicine investigators shows that one specific set of antibodies that is induced naturally by gut beneficial bacteria can be transferred from mothers to infants through breast milk and help infants defend...

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model of lipid scrambling in cell membrane

A class of proteins known as TMEM16 scramblases permit rearrangement of lipids in the cell membrane chiefly by thinning the membrane, according to a new model by Weill Cornell Medicine investigators. The model, based on the highest-resolution images to date of a TMEM16 scramblase, challenges the prevailing theory of how these proteins play their fundamental role in biology and could lead to the first scramblase-targeted pharmaceuticals. 

Scramblase proteins reside in the outer...

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two men holding a large check

A promising venture that hopes to develop a new drug therapy for colorectal cancer won $50,000 in funding and recognition from experienced venture capitalists on May 26 at the annual Biomedical Business Plan Challenge.

The venture, Culnexin Therapeutics, is based on the work of Dr. Pengbo Zhou, a professor of pathology and laboratory medicine at Weill Cornell Medicine. Dr. Zhou is an expert on tiny enzymes...

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illustration of the covid virus

SARS-CoV-2 infections of women in late pregnancy frequently spread to their placentas and led to inflammation, according to a study from investigators at Weill Cornell Medicine and NewYork-Presbyterian. The findings suggest that further research is needed on the virus’s effects in pregnancy and underscore the current recommendation by the U.S. Centers for Disease Control and Prevention that pregnant women continue to take precautions, such as masking, social distancing and vaccination, to...

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illustration of prostate cancer cells

Researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have identified a previously unrecognized form of hormone therapy-resistant prostate cancer, as well as a set of molecules that drive its growth. This discovery opens the door to the development of therapies that treat this specific disease.

In the study, published May 27 in Science, the researchers examined the molecular...

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students at graduation reciting the Hippocratic oath.

Video of Congratulations to the Class of 2022 | Weill Cornell Medicine

Dr. Meridith Pollie was always interested in math and science, but a volunteer opportunity working and bonding with patients at a long-term health care facility inspired her to dedicate those passions in service of others.  

“I realized that I got a whole different kind of fulfillment from building relationships with people...

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students in Qatar graduating from medical school

Weill Cornell Medicine-Qatar awarded Cornell University medical degrees to 41 new doctors on May 11 during the college’s first graduation ceremony held in person since the beginning of the COVID-19 pandemic.

This year’s 41 graduates—comprising 23 men and 18 women—brings the total number of new physicians educated by WCM-Q to 504 since its first graduation ceremony in 2008. The Class of 2022, the college’s 15th graduating class, also represents 16 nationalities; 12 students are Qatari...

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illustration of t cells

Immunotherapy unleashes the power of the immune system to fight cancer. However, for some patients, immunotherapy doesn’t work, and new research may help explain why. When immune cells called T lymphocytes infiltrate malignant tumors, the genetic program of those T cells and the developmental path they then follow, may affect their response to immunotherapy and predict overall patient survival, according to a new study by Weill Cornell Medicine investigators. The results overturn the...

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microscopic image

Tumors can force neighboring cells into supporting cancer growth by releasing lactate into their local environment, according to researchers at Weill Cornell Medicine. The findings pave the way for future drug treatments that thwart that defense mechanism to help cancer patients.

In the study, published May 10 in Cell Reports, the researchers determined how tumors, as they develop, recruit nearby cells...

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illustration of microscopic tuberculosis bacteria

Weill Cornell Medicine researchers have identified a protein in Mycobacterium tuberculosis (Mtb) that contributes to drug tolerance, a phenomenon that allows bacteria to survive treatment with drugs that would normally kill them.

The study, published April 22 in Nature Communications, found that an Mtb protein called CinA reduces the efficacy of isoniazid and other antibiotics used to treat tuberculosis.

“This study...

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diversity week award winners

Weill Cornell Medicine honored a dozen faculty, trainees, students and staff April 25 for their outstanding service and leadership in promoting diversity at the academic medical institution.

The annual Diversity Awards, this year hosted virtually, honor exemplary contributions through research, clinical care, community service and advocacy to improve the health of populations that historically have had unequal access to care. They also recognize excellence in mentorship...

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medical students all seated together

When she was 5 years old, Reine Ibala and her family moved to the United States as refugees amid civil war in their native Republic of the Congo. Her father later developed hypertension and faced challenges as he navigated the U.S. health care system. His physician was dismissive, Ibala recalled, and failed to address the real, personal and cultural reasons behind her father’s misgivings about his treatment plan. With a discordant patient-physician relationship and lack of shared decision-...

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