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composite image of three doctors

Three distinguished Weill Cornell Medicine physician-scientists, Dr. Joseph J. Fins, Dr. Rainu Kaushal and Dr. Shahin Rafii, have been elected to the esteemed Association of American Physicians (AAP).

Regarded as one of the top honors in the field of health and medicine, election to the AAP recognizes physician-scientists exhibiting excellence in the pursuit of medical knowledge and advancing basic or translational science discoveries and their use in...

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syringes

Among participants who had hepatitis C and who injected drugs, those treated at a non-stigmatizing “accessible care” treatment center co-located with a syringe service program (SSP) were nearly three times more likely to be cured of the infectious disease compared with those referred out to local clinicians through patient navigation, according to a randomized clinical trial led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, NYU Grossman School of Medicine...

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a vector image of floating diverse colorful heads

Five Weill Cornell Medicine faculty members have been awarded research funding from the Pilot Grant Program of the Mastercard Diversity-Mentorship Collaborative at Weill Cornell Medicine.

Established through the support of a $5 million grant from the Mastercard Impact Fund, the Mastercard Diversity-Mentorship Collaborative aims to build on Weill Cornell Medicine’s foundational mission of enhancing diversity and inclusion in medicine and establish an infrastructure of mentorship that...

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image of paintbrush labeled c-Maf painting blood vessels

Researchers at Weill Cornell Medicine have identified a key protein that induces the program to build specialized liver blood vessels. The discovery could lead to engineered replacement hepatic tissue to treat common liver diseases.

There are many types of blood vessels in the human body that are functionally different from each other. In the liver, these vessels are organized into distinct zones marked by “zip codes,” which are designated by the expression of specific proteins....

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illustration dta

Using cutting-edge techniques, Weill Cornell Medicine and Memorial Sloan Kettering investigators have visualized the structure of a receptor targeted by an anti-cancer immunotherapy. The new information may help scientists improve this type of cancer treatment.

The study, published Feb. 25 in Science Advances, used cryo-electron microscopy (cryo-EM) to reveal the full-length structure of the glucocorticoid-induced tumor...

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someone receiving anesthesia

Anesthesiology prices jump significantly after medical facilities contract with corporate physician management companies – especially those backed by private equity firms – and threaten to hike patient costs, according to new research by Weill Cornell Medicine and Columbia University Mailman School of Public Health investigators. 

The paper, published...

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physicians standing on a street

A patient living with HIV who received a blood stem cell transplant for high-risk acute myeloid leukemia has been free of the virus for 14 months after stopping HIV antiretroviral drug treatment, suggesting a cure, according to the Weill Cornell Medicine physician-scientists who performed the transplant and managed her care. As in two other successful cases that have been reported, the transplanted donor cells bore a mutation that makes them resistant to HIV infection.

The new case of...

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illustration of diverse group of people

A multi-institutional group in New York City has united to address health disparities in multiple chronic diseases through a new collaborative center.

The vision of the Center to Improve Chronic Disease Outcomes through Multi-level and Multi-generational Approaches Unifying Novel Interventions and Training for Health Equity (COMMUNITY Center) is rooted in public health tenets, recognizing that medical advances alone can only partially reduce the outpaced burden of disease on racial and...

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Abstract illustration of a brain

By mapping all the protein interactions of a dementia-linked protein in the brain called Tau, a team of Weill Cornell Medicine investigators has created a road map for identifying potential new treatment targets for Alzheimer’s disease and related dementia.

Tau protein has long been implicated in neurodegenerative diseases. Mutations in the gene that encodes the Tau protein result in neurodegenerative conditions like frontotemporal dementia, while in Alzheimer’s disease...

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illustration of the lymphatic system

Melanoma cells release small extracellular packages containing the protein nerve growth factor receptor, which primes nearby lymph nodes for tumor metastases, according to a new study by Weill Cornell Medicine investigators.

The study results, published on Nov. 25 in Nature Cancer, may one day help doctors determine which patients need more aggressive treatment and could help with the development of new therapies, said...

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a woman at the doctors holding her stomach while pregnant

COVID-19 vaccination of expectant mothers elicits levels of antibodies to the SARS-CoV-2 outer “spike” protein at the time of delivery that don’t vary dramatically with the timing of vaccination during pregnancy and thus don’t justify delaying vaccination, according to a study from researchers at Weill Cornell Medicine and NewYork-Presbyterian.

The researchers, whose...

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image of someone getting a flu shot

A team led by scientists at Weill Cornell Medicine, Scripps Research and the University of Chicago has identified an important site of vulnerability on influenza viruses—a site that future influenza vaccines and antibody therapies should be able to target to prevent or treat infections by a broad set of influenza strains.

The scientists, whose ...

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Riggio Scholarship

Building on their longtime commitment to social justice, equity and diversity, Louise and Leonard Riggio have made a $5.6 million gift to Weill Cornell Medicine to establish a named scholarship for medical students with financial need who are Black. This scholarship, which will be awarded as part of Weill Cornell Medicine’s debt-free scholarship program for all financially eligible medical students, will cover the full cost of attendance for all four years of medical school. 

The...

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Dr. Elizabeth Ross

Weill Cornell Medicine researchers are using machine learning, a form of artificial intelligence, to shed light on genetic mutations associated with spina bifida. In this birth defect, the neural tube that forms the spinal cord during pregnancy, does not close so that spinal nerves are exposed, resulting in paralysis and high risk of other complications.

Their new study, published online Dec. 16 in PNAS, “brings us closer to...

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a younger and older adult sitting beside each other

Investigators at Weill Cornell Medicine have identified significant differences in the molecular characteristics of tumors from younger and older cancer patients across several cancer types.

Their research, published Dec. 7 in Cell Reports, suggests that cancer treatment could potentially be tailored by age. The study also identified pre-existing drugs that could target mutations predominantly found in...

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iv fluid pictured at a hospital. Credit: Shutterstock

A new protein variant underlies the ability of gastric cancers to resist an otherwise effective family of chemotherapy drugs, according to a study by a multidisciplinary team at Weill Cornell Medicine. The results suggest a treatment strategy that could improve the prognoses of many patients with cancer.

The study, published Oct. 20 in Developmental Cell, and led by co-first authors, Drs. Prashant...

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stock image of brain

Pound for pound, the brain consumes vastly more energy than other organs, and, puzzlingly, it remains a fuel-guzzler even when its neurons are not firing signals called neurotransmitters to each other. Now researchers at Weill Cornell Medicine have found that the process of packaging neurotransmitters may be responsible for this energy drain.

In their study, reported Dec. 3 in Science Advances, they identified tiny...

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Inflammatory immune cells in the spinal cord of mouse

A group of immune cells that normally protect against inflammation in the gastrointestinal tract may have the opposite effect in multiple sclerosis (MS) and other brain inflammation-related conditions, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian researchers. The results suggest that countering the activity of these cells could be a new therapeutic approach for such conditions.

The researchers, who reported their finding Dec. 1 in...

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multicolor dots representing different microglial cell states

A gene mutation linked to Alzheimer’s disease alters a signaling pathway in certain immune cells of individuals with the disease, according to a new study by scientists at Weill Cornell Medicine. The team also found that blocking the pathway—with a drug that’s currently being tested in cancer clinical trials—protects against many features of the condition in a preclinical model. The results could lead to new strategies to block the development of Alzheimer’s disease or slow its progression...

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a stock image of antibodies

Antibody protection against harmful forms of fungi in the gut may be disrupted in some patients with Crohn’s disease—a condition caused by chronic inflammation in the bowel—according to a new study by Weill Cornell Medicine investigators.

Previous studies have shown that the immune system plays a key role in maintaining a healthy balance of gut bacteria. In the new study, published Nov. 22 in Nature Microbiology, senior...

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