News & Events

A multi-institutional team of scientists, led by researchers at Weill Cornell Medicine’s Gale and Ira Drukier Institute for Children's Health, have received a five-year $8.297 grant to continue funding a Center for Lupus Research. The grant, awarded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health, will allow researchers to...

Endothelial cells—the cells that line blood vessels—grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study by Weill Cornell Medicine investigators found.

A growing body of evidence suggests that genetic mutations are not enough to cause cancer; tumor cells also need the right environment to grow. The new...

Neurons that sense pain protect the gut from inflammation and associated tissue damage by regulating the microbial community living in the intestines, according to a study from researchers at Weill Cornell Medicine.

The researchers, whose report appears Oct. 14 in Cell, found in a preclinical model that pain-sensing neurons in the gut secrete a molecule called substance P, which appears to protect against gut...

A mitochondrial gene plays a crucial role in genetic susceptibility to Zika, Dengue, and SARS-CoV-2 infections, a study by Weill Cornell Medicine investigators showed.

The study, published Oct. 6 in Cell Stem Cell, provides proof of principle that cell-based genome-wide association studies (GWAS) could be a valuable tool for studying genetic susceptibility to infections and other diseases. Genome-wide...

Two genes working in concert sustain the integrity of healthy blood vessels, Weill Cornell Medicine investigators discovered in new research. The findings could lead to new approaches treating cardiovascular disease or other inflammatory conditions.

The preclinical study, published Oct. 6 in Nature Cardiovascular Research, shows that the transcription factors ERG and FLI1 work together to shepherd the blood...

A cellular process known as autophagy that helps rid cells of debris may be impaired in pregnant women who go on to develop post-partum depression (PPD), according to new research from Weill Cornell Medicine, Johns Hopkins University School of Medicine and UVA Health investigators.

“Our research indicates that autophagy may be dampened in pregnant women who...

The psychedelic drugs LSD and psilocybin activate serotonin receptors on brain cells in a way that reduces the energy needed for the brain to switch between different activity states, according to a study led by Weill Cornell Medicine researchers.

The study, which appeared Oct. 3 in Nature Communications, offers insight into the mechanism of these drugs’ effects—effects that many hope can someday be harnessed...

Dr. Asim Shahid, a leading pediatric neurologist who specializes in the treatment of childhood epilepsy, has been named chief of the Division of Pediatric Neurology at NewYork-Presbyterian Brooklyn Methodist Hospital. Dr. Shahid was also recruited to Weill Cornell Medicine as an interim assistant professor of clinical pediatrics.

In his new role, Dr. Shahid will expand and enhance NewYork-Presbyterian Brooklyn Methodist Hospital’s world-class pediatric neurology and epilepsy services,...

For the fifth consecutive year, NewYork Quality Care, the accountable care organization (ACO) of NewYork-Presbyterian, Columbia University Irving Medical Center and Weill Cornell Medicine, has earned shared savings in the Centers for Medicare & Medicaid Services (CMS) Medicare Shared Savings Program. In 2021, NewYork Quality Care saved Medicare $26,335,014 while providing high quality care for more than 35...

The presence of some fungal species in tumors predicts—and may even help drive—worse cancer outcomes, according to a study from Weill Cornell Medicine and Duke University researchers.

The study, which appears Sept. 29 in Cell, provides a scientific framework to develop tests that delineate specific fungal species in tumors that are relevant for prediction of cancer progression and therapy. The results also point to...

A new screening tool for electronic medical records accurately identifies patients who are at high risk of having or developing progressive scarring of the lungs, a condition called idiopathic pulmonary fibrosis, according to investigators from Weill Cornell Medicine, NewYork-Presbyterian, the University of Chicago, Brigham and Women’s Hospital and Mayo Clinic.

Idiopathic pulmonary fibrosis (IPF) is usually fatal, in part because it tends to be diagnosed late in its course, when...

By analyzing key enzymes in a new way, an international team led by researchers at Weill Cornell Medicine has discovered how a well-known signaling molecule can either stimulate or suppress tumor growth depending on where it’s produced. The work, published Sept. 27 in Cell Reports, reveals a new aspect of tumor cell biology, and points to a promising strategy for treating many types of...

An advanced software tool for analyzing DNA sequences from tumor samples has uncovered likely new cancer-driving genes, in a study led by Weill Cornell Medicine researchers.

In the study, published Sept. 26 in Nature Communications, the researchers designed the software, known as CSVDriver, to map and analyze the locations of large mutations, known as structural variants (SVs), in tumor DNA datasets. They then applied the...

A common, spontaneous mutation in blood stem cells, which has been linked to higher risks of blood cancer and cardiovascular disease, may promote these diseases by altering the stem cells’ programming of gene activity and the mix of blood cells they produce, according to a study co-led by investigators at Weill Cornell Medicine, NewYork-Presbyterian, the New York Genome Center...

Aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson’s disease through a cellular waste-ejection process, suggests a new study led by Weill Cornell Medicine researchers.

During the process, called lysosomal exocytosis, neurons eject protein waste they cannot break down and recycle. The discovery, published Aug. 22 in Nature Communications, could resolve one of the mysteries...

Weill Cornell Medicine investigators have identified definitive biological links between African ancestry and disease processes that affect an aggressive cancer type called triple-negative breast cancer (TNBC). Their analysis of TNBC tumors from a diverse patient population yielded a large set of genes whose expression differed in patients with African ancestry compared with patients with European ancestry.

In the...

A collaboration between Weill Cornell Medicine scientists and other leaders in Alzheimer’s disease research has revealed widespread metabolic changes in the brains of individuals with Alzheimer’s disease. The findings could lead to the development of new treatments aimed at ameliorating the metabolic effects of the disease.

For the study, published July 13 in Alzheimer’s and Dementia, the investigators...

An easy-to-use device for infant circumcision has proved to be safe in an international randomized controlled clinical trial led by Weill Cornell Medicine physician-scientists. The results suggest that the device could boost efforts to increase circumcision rates and prevent HIV in low-resource settings where early infant circumcision is not widespread. 

The trial, whose results were...

Tampa FL (Sept. 13, 2022) – Artificial intelligence may soon help doctors diagnose and treat diseases, including cancer and depression, based on the sound of a patient’s voice, as 12 leading research institutions launch a landmark National Institutes of Health-funded academic project that may establish voice as a biomarker used in clinical care.

The University of South Florida in Tampa, FL, is the lead institution on the project in collaboration with...

NEW YORK (Sept. 9, 2022)—Weill Cornell Medicine was awarded a $61.9 million grant from the National Institutes of Health’s National Center for Advancing Translational Sciences (NCATS) to continue funding its Clinical and Translational Science Center (CTSC) until 2027. It is the largest federal grant ever awarded to Weill Cornell Medicine and the fourth consecutive time this initiative has been funded by the NIH, representing...