News & Events

As part of a National Institutes of Health initiative to improve maternal health and pregnancy outcomes nationwide, Weill Cornell Medicine and NewYork-Presbyterian will play a pivotal role as collaborators with Columbia University Irving Medical Center (CUIMC) as one of 10 nationwide IMPROVE (Implementing a Maternal Health and Pregnancy Outcomes Vision for Everyone)...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers at Weill Cornell Medicine and RMIT University in Australia have discovered that ion channels called BK channels have unique openings in their sides, which drug molecules may be able to access. The...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill Cornell Medicine. The discovery is a significant advance in cell biology, likely solves a long-standing mystery about an unusual feature of some ion channels and has implications for the development of drugs targeting these proteins and for drug delivery.

Ion channels are ubiquitous in the...

An international phase 3 clinical trial, done in participation with Weill Cornell Medicine and NewYork-Presbyterian, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer that overexpressed a specific biomarker.

Results from the GLOW study, published July 31 in Nature Medicine, together...

A study led by researchers at Memorial Sloan Kettering Cancer Center (MSK) and Weill Cornell Medicine discovered a new relationship between cancer cells and the immune system, and shows how cancer can selfishly hijack a normally helpful immune pathway.

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body’s immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators. The finding could help explain symptoms of prolonged inflammation and “long COVID” in people who have had the disease.

The research team, led by...

Watch the full Class of 2027 White Coat Ceremony on YouTube.

Nick Rosenfeld’s passion for medicine is profoundly personal, as is his desire for cultivating enduring relationships with patients...

A technique that enables scientists to record gene mutations and patterns of gene activity in individual cells has been extended to cover RNA splicing as well, in a study led by researchers at Weill Cornell Medicine, the New York Genome Center and the Princess Margaret Cancer Centre in Toronto. A better understanding of how aberrations in this process affects the development and behavior of...

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy. A new, very precise gene-editing tool created by Weill Cornell Medicine investigators will enable scientists to study the impact of these specific genetic changes in preclinical models rather than being limited to more broadly targeted tactics, such as deleting the entire gene.

The tool was...

Pregnant individuals who had a previous COVID-19 infection and received a full course of COVID-19 vaccination and a booster have the strongest immune protection from the disease – and pass that protection along to their unborn babies, according to a new study from Weill Cornell Medicine and The Rockefeller University investigators.

The researchers, whose study published Aug. 10 in Nature Communications, examined pregnant...

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study conducted by researchers at Weill Cornell Medicine and the Burke Neurological Institute.

In the study, published Aug. 9 in the British Journal of Anaesthesia, the first-in-class drug conceptualized by lead author...

While there are highly effective treatments for the hepatitis C virus (HCV), only 1 in 5 Medicaid enrollees diagnosed with HCV started treatment, according to a retrospective study led by researchers at Weill Cornell Medicine and Cornell University’s Ithaca campus. The findings revealed that treatment uptake rates were even lower among people under 30, women, Hispanic and Asian individuals, as well as people who inject drugs. The research underscores the urgent need for public health and...

Dr. Gregory F. Sonnenberg, The Henry R. Erle, M.D.-Roberts Family Associate Professor of Medicine and head of basic research in Gastroenterology and Hepatology at Weill Cornell Medicine, has been awarded a $3.26 million, five-year MERIT grant from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to investigate the underlying mechanisms of inflammatory...

A multi-institutional team of scientists led by Dr. Mario Gaudino, the Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery and assistant dean for clinical trials at Weill Cornell Medicine, has been approved for a nearly $30 million funding award from the Patient-Centered Outcomes Research Institute (PCORI). The award will fund the first study among women and Black and Hispanic patients comparing the effectiveness of...

The availability of generic antiviral drugs to manage chronic hepatitis B resulted in significant savings to Medicare, despite an increase in prescriptions, according to an analysis by researchers at Weill Cornell Medicine and NewYork-Presbyterian. The findings were published July 8 in Gastroenterology.

About 1.6 million people in the United States live with chronic hepatitis B. There is no cure...

During the COVID-19 pandemic, many U.S. hospitals had overcapacity intensive care units (ICU) while other area hospitals had open ICU beds available, a phenomenon known as “load imbalance.” The hospitals most likely to be overloaded in imbalanced regions served a higher number of Black patients and more patients enrolled in Medicaid, according to a new study conducted by Weill Cornell Medicine investigators.

In the...

Using an innovative method for measuring doctor turnover, Weill Cornell Medicine researchers determined that between 2010 and 2018, the annual rate at which physicians left their practices increased by 43 percent, from 5.3 percent to 7.6 percent a year.  The causes of this trend are not known, but warrant further investigation, according to the researchers.

The study, published July 11 in the Annals of Internal Medicine, also found that...

Breastfeeding and pumping are widely recognized as beneficial for both mother and child. However, due to ability of both to burn calories, some women may excessively breastfeed and pump as a method of weight control, according to a new paper by investigators at Weill Cornell Medicine and Yale School of Medicine. Women with a history of an eating disorder or a current eating disorder are likely at particular risk, the investigators note. They posit that breastfeeding and pumping in this way...

State laws allowing medical cannabis use did not reduce prescriptions for opioids or other therapies for chronic, non-cancer pain, according to a policy analysis by Weill Cornell Medicine investigators.

Dr. Beth McGinty, chief of the Division of Health Policy and Economics at Weill Cornell Medicine, used a study design that emulates a clinical trial to analyze the effects of medical cannabis laws on...

An atlas that catalogues gene activity and the levels of small molecules called metabolites in tumor samples offers a new way of identifying the deep mechanisms of cancer, according to researchers at Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center.

The researchers, who published their work June 19 in Nature Metabolism, created the Cancer Atlas of Metabolic Profiles (CAMP) by combining new and existing...