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Weill Cornell Medicine is part of an international team that has been awarded funding of up to $25 million over five years by Cancer Grand Challenges to study the causes of cancer inequities.

Cancer Grand Challenges is a global funding initiative co-founded by the National Cancer Institute and Cancer Research UK that aims to address key challenges in cancer biology and patient care.

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male breast cancer

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing analysis of male breast cancer, which looked at the complete DNA landscape of tumor samples from 10 patients.

This is an important step in viewing breast cancer in men, which represents less than 1 percent of all breast cancer cases each year, as a unique disease...

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image of Mycobacterium tuberculosis

Patients who have drug-resistant tuberculosis (TB) have a similar microbiological response to bedaquiline-based second-line medications as patients with drug-sensitive TB taking first-line regimens, according to researchers at Weill Cornell Medicine in New York and GHESKIO in Haiti. Second-line medications are those that are given when one or more of the drugs given first for the disease are not effective. The research could have implications for...

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gene signature non-small cell lung cancer


A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation. The results, published in Cell Medicine Reports on Feb. 23, suggested that this “gene signature” could be used to identify a subclass of lung tumors that is more likely to be eradicated...

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eating disorder

Individuals with eating disorders who have low income are frequently misdiagnosed and lack adequate access to appropriate therapy, according to researchers from Weill Cornell Medicine and Columbia University Vagelos College of Physicians and Surgeons.

Their...

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doctor giving a patient a bottle of pills

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine’s mechanism of action has been unclear. Now researchers at the Jill Roberts Center for IBD and the Jill Roberts Institute for Research in IBD at Weill Cornell Medicine and...

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Dr. Juan Pascual

NEW YORK (Feb. 16, 2023)—Dr. Juan Pascual, a leading pediatric neurologist, has been appointed chief of the Division of Child Neurology in the Department of Pediatrics at NewYork-Presbyterian Komansky Children’s Hospital and Weill Cornell Medicine, effective March 1.

 In his new role, Dr. Pascual will oversee the child and neonatal neurology divisions with a focus on increasing access to high-quality care, expanding scientific research, and recruiting and developing...

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ribbon drawing of the CLC-ec1 transporter

Structural rearrangements allow pH-dependent activation of CLC-e1. The video depicts the molecular movements of the CLC transporter from the inactive state to its two active conformations.

The molecular workings of a family of important but hard-to-study proteins called CLCs have been illuminated as never before in a study led by researchers at Weill Cornell Medicine.

CLCs play fundamental roles in biology by regulating the levels of chloride and other ions in...

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Headshot of a woman against a gray backdrop

NEW YORK (February 13, 2023) Dr. Jennie G. Ono, a leading pediatrician who focuses on inpatient care, newborn medicine and pediatric asthma, has been appointed chief of pediatrics at NewYork-Presbyterian Queens. Dr. Ono also serves as an associate professor of clinical pediatrics at Weill Cornell Medicine.

In her new role, Dr. Ono will continue to grow the pediatric primary care, subspecialty and inpatient programs at...

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Drukier Prize event

NEW YORK (Feb. 13, 2024) — Dr. Sumit Gupta, a physician-scientist whose research focuses on vulnerable subpopulations of children with cancer, has been awarded the eighth annual Gale and Ira Drukier Prize in Children’s Health Research, Weill Cornell Medicine announced today. 

The Drukier Prize honors an early-career pediatrician whose research promises to make significant contributions toward improving the health of children and adolescents. Dr. Gupta is an associate...

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Headshot of a woman against a gray backdrop

NewYork-Presbyterian/Weill Cornell Medical Center has received the Mitral Valve Repair Reference Center Award from the American Heart Association and the Mitral Foundation for a demonstrated record of superior clinical outcomes resulting from evidence-based, guideline-directed degenerative mitral valve repair.

This award recognizes NewYork-Presbyterian/Weill Cornell Medical Center’s contribution to advancing best practices in the surgical treatment of mitral valve disease...

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lung cancer histological transformation

Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers at Weill Cornell Medicine have developed a mouse model that illuminates this problematic process, known as histological transformation. The findings advance the understanding of how mutated genes can trigger cancer evolution and suggest targets for more effective...

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A woman smiling

Video of Breast Cancer Precision Care: A Family Affair | Weill Cornell Medicine

When Nila Charles was diagnosed with breast cancer, she was the mother of two young children, working long hours and caring for a family member who was also diagnosed with cancer.

"It was a tough time, but I rallied through it," Charles recalled...

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CMV mRNA vaccine

An experimental mRNA vaccine against human cytomegalovirus (CMV), a common virus that can infect babies during pregnancy, elicited some of the most promising immune responses to date of any CMV vaccine candidate, according to a study by Weill Cornell Medicine investigators.

The study, published in the Journal of Infectious Diseases on Feb. 7, provided evidence...

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illustration of blood vessels leading to the brain

More than a decade ago, the anticoagulant apixaban, trade name Eliquis, was shown to be superior to aspirin for preventing recurrent stroke in patients with a heart condition called atrial fibrillation. But a multi-center, phase 3 clinical trial has found that apixaban is no more effective than aspirin at preventing a second stroke in patients diagnosed with a milder, related condition called atrial cardiopathy, according to results reported by researchers at Weill Cornell Medicine, Columbia...

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Dr. Alessio Accardi

Dr. Alessio Accardi, professor of physiology and biophysics in anesthesiology at Weill Cornell Medicine, has been awarded a five-year, $2.7 million grant by the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health (NIH), for fundamental research on cell membrane proteins that have critical roles in biology and are involved in numerous human diseases.

The grant is a much-sought...

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Dr. Kuhn

NEW YORK (Jan. 31, 2024)—Dr. Bernhard Kühn, a leading physician-scientist who specializes in heart regeneration, has been named chief of the Division of Cardiology in the Department of Pediatrics at Weill Cornell Medicine and NewYork-Presbyterian Komansky Children’s Hospital, effective Feb. 1.

In his role as chief, Dr. Kühn will lead a skilled team of physicians and scientists committed to enhancing the division’s...

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Dr. Jeannine Gerhardt

Dr. Jeannine Gerhardt, an assistant professor of stem cell biology in obstetrics and gynecology and in reproductive medicine at Weill Cornell Medicine, has received a five-year, $2.1 million grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health, for the study of repetitive DNA and RNA sequences and the mechanisms by which they cause cell dysfunction and diseases.

The NIGMS Maximizing Investigators’ Research Award is intended to...

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photo of mosquito feeding on a human

Structural insights into a potent antimalarial drug candidate’s interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

The antimalarial molecule, TDI-8304, is one of a new class of experimental therapeutics that targets the proteasome, an essential, multiprotein complex in P. falciparum...

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dopamine neuron senescence after COVID infection

A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers from Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and Columbia University Vagelos College of Physicians and Surgeons suggest that further research on this finding may shed light on the neurological symptoms associated with long COVID such as brain fog, lethargy and depression....

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